diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 19d29b408ba..763a6923a62 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -4711,7 +4711,7 @@ consensus sequences.")
          "10k88i1fcqchrrjv82rmylwvbwqfba0n51palhig9hsg71xs0dbi"))
        ;; Delete bundled binary
        (snippet '(delete-file "libs/ccs"))))
-    (build-system python-build-system)
+    (build-system pyproject-build-system)
     (arguments
      `(#:phases
        (modify-phases %standard-phases