diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 9f1913d87d5..cd5455a841b 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -18755,58 +18755,66 @@ Mixtures.")
 
 ;; Needed for r-liana
 (define-public r-omnipathr/devel
-  (let ((commit "679bb79e319af246a16968d27d64d8d6937a331a")
-        (revision "1"))
-    (package
-      (name "r-omnipathr")
-      (version (git-version "3.5.5" revision commit))
-      (source (origin
-                (method git-fetch)
-                (uri (git-reference
-                      (url "https://github.com/saezlab/omnipathr")
-                      (commit commit)))
-                (file-name (git-file-name name version))
-                (sha256
-                 (base32
-                  "10h6lyapyx4ik8r4kx5z2dly46jlf2v57caq4g6i0hzifyz2vgjq"))))
-      (properties `((upstream-name . "OmnipathR")))
-      (build-system r-build-system)
-      (arguments
-       `(#:phases
-         (modify-phases %standard-phases
-           (add-after 'unpack 'set-HOME
-             (lambda _ (setenv "HOME" "/tmp"))))))
-      (propagated-inputs
-       (list r-checkmate
-             r-crayon
-             r-curl
-             r-digest
-             r-dplyr
-             r-httr
-             r-igraph
-             r-jsonlite
-             r-later
-             r-logger
-             r-magrittr
-             r-progress
-             r-purrr
-             r-rappdirs
-             r-readr
-             r-readxl
-             r-rlang
-             r-rvest
-             r-stringr
-             r-tibble
-             r-tidyr
-             r-tidyselect
-             r-withr
-             r-xml2
-             r-yaml))
-      (native-inputs (list r-knitr r-testthat))
-      (home-page "https://github.com/saezlab/omnipathr")
-      (synopsis "OmniPath web service client and more")
-      (description
-       "This package provides a client for the OmniPath web service and many
+  (package
+    (name "r-omnipathr")
+    (version "3.15.3")
+    (source (origin
+              (method git-fetch)
+              (uri (git-reference
+                    (url "https://github.com/saezlab/omnipathr")
+                    (commit (string-append "v" version))))
+              (file-name (git-file-name name version))
+              (sha256
+               (base32
+                "0sq32s3v7q5w9zym54fm0ws1d1wnwyhczazyk9g722ydx2zvbls4"))))
+    (properties `((upstream-name . "OmnipathR")))
+    (build-system r-build-system)
+    (arguments
+     `(#:phases
+       (modify-phases %standard-phases
+         (add-after 'unpack 'set-HOME
+           (lambda _ (setenv "HOME" "/tmp"))))))
+    (propagated-inputs
+     (list r-checkmate
+           r-crayon
+           r-curl
+           r-digest
+           r-dplyr
+           r-fs
+           r-httr2
+           r-igraph
+           r-jsonlite
+           r-later
+           r-logger
+           r-lubridate
+           r-magrittr
+           r-progress
+           r-purrr
+           r-r-utils
+           r-rappdirs
+           r-readr
+           r-readxl
+           r-rlang
+           r-rmarkdown
+           r-rsqlite
+           r-rvest
+           r-sessioninfo
+           r-stringi
+           r-stringr
+           r-tibble
+           r-tidyr
+           r-tidyselect
+           r-vctrs
+           r-withr
+           r-xml
+           r-xml2
+           r-yaml
+           r-zip))
+    (native-inputs (list r-knitr r-testthat))
+    (home-page "https://github.com/saezlab/omnipathr")
+    (synopsis "OmniPath web service client and more")
+    (description
+     "This package provides a client for the OmniPath web service and many
 other resources.  It also includes functions to transform and pretty print
 some of the downloaded data, functions to access a number of other resources
 such as BioPlex, ConsensusPathDB, EVEX, Gene Ontology, Guide to
@@ -18816,7 +18824,7 @@ RegNetwork, ReMap, TF census, TRRUST and Vinayagam et al. 2011.  Furthermore,
 OmnipathR features a close integration with the NicheNet method for ligand
 activity prediction from transcriptomics data, and its R implementation
 @code{nichenetr}.")
-      (license license:expat))))
+    (license license:expat)))
 
 (define-public r-liana
   (let ((commit "10d81773e0874de676eb106ce56e3cf9d4fe01d3")