diff --git a/doc/guix.texi b/doc/guix.texi
index af91f02d1f1..9aadad4c2ea 100644
--- a/doc/guix.texi
+++ b/doc/guix.texi
@@ -144,6 +144,7 @@ Copyright @copyright{} 2024 Evgeny Pisemsky@*
 Copyright @copyright{} 2025 jgart@*
 Copyright @copyright{} 2025 Artur Wroblewski@*
 Copyright @copyright{} 2025 Edouard Klein@*
+Copyright @copyright{} 2025 Rodion Goritskov@*
 
 Permission is granted to copy, distribute and/or modify this document
 under the terms of the GNU Free Documentation License, Version 1.3 or
@@ -35700,6 +35701,80 @@ The file which should store the logging output of Agate.
 @end table
 @end deftp
 
+@subsubheading Miniflux
+
+@cindex miniflux
+The @uref{https://miniflux.app/, Miniflux} is a minimalist RSS feed reader
+with a web interface.
+
+Depending on the configuration, an initial administrator user can be pre-created
+on startup. To enable this, @code{create-admin?} should be set to @code{#t}, and
+both @code{admin-username-file} and @code{admin-password-file} should point to
+files containing the username and password, respectively. However, it is
+recommended to manually change the password to a secure one via the web
+UI after the initial service startup.
+
+@defvar miniflux-service-type
+This is the type of the Miniflux service. Its value
+must be a @code{miniflux-configuration} record as in this example:
+
+@lisp
+(service miniflux-service-type
+         (miniflux-configuration
+          (listen-address "0.0.0.0:8080")
+          (base-url "http://my-news-source.test")
+          (create-administrator-account? #t)
+          (administrator-account-name "/var/miniflux/initial-admin-username")
+          (administrator-account-password "/var/miniflux/initial-admin-password")))
+@end lisp
+
+The details of the @code{miniflux-configuration} record type are given below.
+
+@end defvar
+
+@deftp {Data Type} miniflux-configuration
+Available @code{miniflux-configuration} fields are:
+
+@table @asis
+@item @code{listen-address} (default: @code{"127.0.0.1:8080"}) (type: string)
+Address to listen on.
+Use absolute path like @code{"/var/run/miniflux/miniflux.sock"} for a Unix socket.
+
+@item @code{base-url} (default: @code{"http://127.0.0.1/"}) (type: string)
+Base URL to generate HTML links and base path for cookies.
+
+@item @code{create-administrator-account?} (default: @code{#f}) (type: boolean)
+Create an initial administrator account.
+
+@item @code{administrator-account-name} (type: maybe-string-or-file-path)
+Initial administrator account name as a string or an absolute path
+to a file with an account name inside.
+
+@item @code{administrator-account-password} (type: maybe-string-or-file-path)
+Initial administrator account password as a string or an absolute path
+to a file with a password inside.
+
+@item @code{run-migrations?} (default: @code{#t}) (type: boolean)
+Run database migrations during application startup.
+
+@item @code{database-url} (default: @code{"host=/var/run/postgresql"}) (type: string)
+PostgreSQL connection string.
+
+@item @code{user} (default: @code{"miniflux"}) (type: string)
+User name for Postgresql and system account.
+
+@item @code{group} (default: @code{"miniflux"}) (type: string)
+Group for the system account.
+
+@item @code{log-file} (default: @code{"/var/log/miniflux.log"}) (type: string)
+Path to the log file.
+
+@item @code{extra-settings} (type: maybe-list)
+Extra configuration parameters as a list of strings.
+
+@end table
+@end deftp
+
 @node High Availability Services
 @subsection High Availability Services
 
diff --git a/etc/teams.scm b/etc/teams.scm
index 69057e16efa..8a75b68d70e 100755
--- a/etc/teams.scm
+++ b/etc/teams.scm
@@ -1058,8 +1058,8 @@ the \"texlive\" importer."
 (define-member (person "Ludovic Courtès"
                        "ludo@gnu.org"
                        "civodul")
-  core home bootstrap core-packages installer
-  documentation mentors)
+  core core-packages hpc installer
+  mentors)
 
 (define-member (person "Andreas Enge"
                        "andreas@enge.fr"
@@ -1305,7 +1305,7 @@ the \"texlive\" importer."
 
 (define-member (person "Nicolas Graves"
                        "ngraves@ngraves.fr"
-                       "ngraves")
+                       "nicolas-graves")
   javascript python ruby)
 
 (define-member (person "Yelninei"
diff --git a/gnu/home/services/sway.scm b/gnu/home/services/sway.scm
index bf001de1e5a..835053de1af 100644
--- a/gnu/home/services/sway.scm
+++ b/gnu/home/services/sway.scm
@@ -168,7 +168,7 @@
    (lambda (e)
      (or (member e
                  '("no-warn" "whole-window" "border" "exclude-titlebar"
-                   "release" "locked" "inhibited" "no-repeat"))
+                   "release" "locked" "to-code" "inhibited" "no-repeat"))
          (string-prefix? "input-device=" e)))
    lst))
 
@@ -177,7 +177,7 @@
    (lambda (e)
      (or (member e
                  '("no-warn" "whole-window" "border" "exclude-titlebar"
-                   "release" "locked" "to-code" "inhibited" "no-repeat"))
+                   "release" "locked" "inhibited" "no-repeat"))
          (string-prefix? "input-device=" e)))
    lst))
 
diff --git a/gnu/local.mk b/gnu/local.mk
index 43de2994f45..f185f1d7ed9 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -512,7 +512,6 @@ GNU_SYSTEM_MODULES =				\
   %D%/packages/openkinect.scm			\
   %D%/packages/onc-rpc.scm			\
   %D%/packages/opencl.scm			\
-  %D%/packages/openbox.scm			\
   %D%/packages/opencog.scm			\
   %D%/packages/openldap.scm			\
   %D%/packages/openpgp.scm			\
diff --git a/gnu/packages/admin.scm b/gnu/packages/admin.scm
index 3c7bebc189e..fbd4a518e16 100644
--- a/gnu/packages/admin.scm
+++ b/gnu/packages/admin.scm
@@ -601,8 +601,13 @@ interface and is based on GNU Guile.")
                                "/bin/gzip")
                 (string-append "--with-zstd=" #$(this-package-input "zstd")
                                "/bin/zstd")))))
-    (inputs (modify-inputs (package-inputs shepherd-0.10)
-              (append gzip zstd)))))
+    (native-inputs
+     (modify-inputs (package-native-inputs shepherd-0.10)
+       (replace "guile-fibers" guile-fibers))) ;use latest guile-fibers available
+    (inputs
+     (modify-inputs (package-inputs shepherd-0.10)
+       (replace "guile-fibers" guile-fibers) ;use latest guile-fibers available
+       (append gzip zstd)))))
 
 (define-public shepherd shepherd-0.10)
 
@@ -1110,8 +1115,21 @@ on memory usage on GNU/Linux systems.")
         (base32 "058y4a4mvx9m179dyr4wi8mlm6i4ybywshadaj4cvfn9fv0r0nkx"))
        (file-name (git-file-name name version))))
     (build-system gnu-build-system)
+    (arguments
+      (list
+        #:configure-flags
+        #~(list "--enable-sensors")
+        #:phases
+        #~(modify-phases %standard-phases
+            (add-after 'unpack 'patch-dlopen
+              (lambda* (#:key inputs #:allow-other-keys)
+                (substitute* "linux/LibSensors.c"
+                  (("dlopen\\(\"libsensors\\.so")
+                   (string-append "dlopen(\""
+                                  (search-input-file
+                                    inputs "/lib/libsensors.so")))))))))
     (inputs
-     (list ncurses))
+     (list ncurses (list lm-sensors "lib")))
     (native-inputs
      (list autoconf automake python-minimal-wrapper))     ; for scripts/MakeHeader.py
     (home-page "https://htop.dev")
@@ -6294,6 +6312,10 @@ alias cysdig=sudo csysdig --modern-bpf
                              "fail2ban/client/fail2banregex.py")
                 (("/etc/fail2ban")
                  (string-append #$output "/etc/fail2ban")))))
+          (replace 'check
+            (lambda* (#:key tests? test-flags #:allow-other-keys)
+              (when tests?
+                (invoke "./bin/fail2ban-testcases"))))
           (add-after 'fix-default-config 'set-action-dependencies
             (lambda* (#:key inputs #:allow-other-keys)
               ;; deleting things that are not feasible to fix
@@ -6374,7 +6396,8 @@ alias cysdig=sudo csysdig --modern-bpf
                             "fail2ban-regex" "fail2ban-server"
                             "fail2ban-testcases"))
                 ((install-man "5") "jail.conf")))))))
-    (native-inputs (list python-setuptools python-wheel))
+    (native-inputs (list python-aiosmtpd
+                         python-setuptools))
     (inputs (list gawk
                   coreutils-minimal
                   curl
diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index d3d50d30826..75fc119f681 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -2204,26 +2204,38 @@ intended to behave exactly the same as the original BWK awk.")
 (define-public python-bcbio-gff
   (package
     (name "python-bcbio-gff")
-    (version "0.6.9")
+    ;; python-bcbio-gff can only be refreshed manually, because guix refresh
+    ;; does not understand the tags on the github repository.
+    (version "0.7.1")
     (source (origin
-              (method url-fetch)
-              (uri (pypi-uri "bcbio-gff" version))
+              ;; No tests in PyPI package.
+              (method git-fetch)
+              (uri (git-reference
+               (url "https://github.com/chapmanb/bcbb")
+               (commit (string-append "bcbio-gff-v" version))))
+              (file-name (git-file-name name version))
               (sha256
                (base32
-                "1pm1szyxabhn8jismrj9cjhf88ajgcmm39f0cgf36iagw5qakprl"))))
+                "0144xxzibq4mrg8a1w2scs120rd9svq07hm5ccs91n3a4nvwjfsd"))))
     (build-system pyproject-build-system)
+    (arguments
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'build 'enter-directory
+            (lambda _ (chdir "gff"))))))
     (native-inputs
-     (list python-pytest))
+     (list python-setuptools python-pytest))
     (propagated-inputs
      (list python-biopython
-           python-setuptools
-           python-six
-           python-wheel))
+           python-six))
     (home-page "https://github.com/chapmanb/bcbb/tree/master/gff")
     (synopsis "Read and write GFF files with Biopython integration")
     (description
      "This package lets you read and write files in Generic Feature
 Format (GFF) with Biopython integration.")
+    (properties
+     '((upstream-name . "bcbio-gff")))
     (license (license:non-copyleft "http://www.biopython.org/DIST/LICENSE"))))
 
 (define-public python-bcbio-gff/biopython-1.73
@@ -12153,26 +12165,19 @@ interpretation.")
 (define-public python-taggd
   (package
     (name "python-taggd")
-    (version "0.3.6")
+    (version "0.4.0")
     (source (origin
               (method git-fetch)
               (uri (git-reference
-                    (url "https://github.com/SpatialTranscriptomicsResearch/taggd")
+                    (url "https://github.com/jfnavarro/taggd")
                     (commit version)))
               (file-name (git-file-name name version))
               (sha256
                (base32
-                "0j19ah81z7aqrdljah9hyarp91gvgbk63pz6fz3pdpksy1yqyi6k"))
-              (modules '((guix build utils)))
-              (snippet
-               '(for-each delete-file
-                          (find-files "taggd" "\\.c$")))))
+                "17hi1vs1qwhxx8jnradnl9k471li6fjb6w5sljkpzjxy7rkxwb85"))))
     (build-system pyproject-build-system)
     (arguments
      (list
-      #:test-flags
-      ;; AssertionError: 0 is not true : Running Normal BAM test failed.
-      #~(list "-k" "not test_normal_bam_run")
       #:phases
       #~(modify-phases %standard-phases
           (add-before 'check 'remove-local-taggd
@@ -12181,10 +12186,16 @@ interpretation.")
               ;; taggd when running tests.
               (delete-file-recursively "taggd"))))))
     (propagated-inputs
-     (list python-numpy python-pysam))
+     (list python-numpy
+           python-pysam
+           python-tqdm
+           python-aiofiles
+           python-dnaio
+           python-types-aiofiles
+           python-types-tqdm))
     (native-inputs
      (list python-cython python-pytest python-setuptools))
-    (home-page "https://github.com/SpatialTranscriptomicsResearch/taggd")
+    (home-page "https://github.com/jfnavarro/taggd")
     (synopsis "Genetic barcode demultiplexing")
     (description "This package provides TagGD barcode demultiplexing utilities
 for Spatial Transcriptomics data.")
@@ -12193,40 +12204,45 @@ for Spatial Transcriptomics data.")
 (define-public stpipeline
   (package
     (name "stpipeline")
-    (version "1.8.1")
+    (version "2.0.0")
     (source
      (origin
-       (method url-fetch)
-       (uri (pypi-uri "stpipeline" version))
+       (method git-fetch)
+       (uri (git-reference
+              (url "https://github.com/jfnavarro/st_pipeline")
+              (commit version)))
+       (file-name (git-file-name name version))
        (sha256
-        (base32 "0har2g42fvaqpiz66lincy86aj1hvwzds26kxhxfamvyvv4721wk"))))
+        (base32 "1qah9sa7wy9ywf0si2ngqg0qyr9jjp5gxmjx3y65i78bxyq8pfyx"))))
     (build-system pyproject-build-system)
     (arguments
      (list
       #:phases '(modify-phases %standard-phases
-                  (add-after 'unpack 'relax-requirements
-                    (lambda _
-                      (substitute* "requirements.txt"
-                        (("argparse.*")
-                         "")))))))
+                  ;; requirements.txt and pyproject.toml have all versions
+                  ;; of the dependencies hardcoded. All tests pass, so it should
+                  ;; be good enough.
+                  ;; However, the sanity-check of any Python package that has
+                  ;; stpipelines a dependency, would fail too.
+                  (delete 'sanity-check))))
     (propagated-inputs (list htseq
-                             python-cython
-                             python-invoke
+                             python-distance
+                             python-dnaio
                              python-numpy
                              python-pandas
-                             python-pympler
                              python-pysam
                              python-regex
                              python-scikit-learn
                              python-scipy
                              python-seaborn
-                             python-setuptools
-                             python-sqlitedict
                              python-taggd
+                             python-types-regex
                              samtools
                              star))
-    (native-inputs (list python-setuptools python-wheel))
-    (home-page "https://github.com/SpatialTranscriptomicsResearch/st_pipeline")
+    (native-inputs (list
+                    python-cython
+                    python-pytest
+                    python-poetry-core))
+    (home-page "https://github.com/jfnavarro/st_pipeline")
     (synopsis "Pipeline for spatial mapping of unique transcripts")
     (description
      "This package provides an automated pipeline for spatial mapping of
diff --git a/gnu/packages/bootloaders.scm b/gnu/packages/bootloaders.scm
index dbce7075e30..840cce37122 100644
--- a/gnu/packages/bootloaders.scm
+++ b/gnu/packages/bootloaders.scm
@@ -1041,6 +1041,7 @@ CONFIG_TOOLS_KWBIMAGE=n")
             (lambda* (#:key tests? #:allow-other-keys)
               (when tests?
                 (invoke "./u_boot_pylib")))))))
+    (native-inputs (list python-setuptools))
     (synopsis "U-Boot Python library")
     (description "This package provides common Python code used by some of the
 commands part of the U-Boot project, such as Patman.")))
@@ -1076,6 +1077,7 @@ commands part of the U-Boot project, such as Patman.")))
                    ,(dirname (search-input-file
                               inputs
                               "libexec/git-core/git-send-email"))))))))))
+    (native-inputs (list python-setuptools))
     (inputs
      (list git
            `(,git "send-email")
diff --git a/gnu/packages/check.scm b/gnu/packages/check.scm
index 2451fd9d045..4b974917893 100644
--- a/gnu/packages/check.scm
+++ b/gnu/packages/check.scm
@@ -3184,25 +3184,6 @@ JSON APIs with Behave.")
 time by mocking the datetime module.")
     (license license:asl2.0)))
 
-(define-public python-flexmock
-  (package
-    (name "python-flexmock")
-    (version "0.12.2")
-    (source (origin
-              (method url-fetch)
-              (uri (pypi-uri "flexmock" version))
-              (sha256
-               (base32
-                "18dcr7mpldf3cxsqi9rak75n4z7x3j544l4ixdspairm7cf6cp23"))))
-    (build-system pyproject-build-system)
-    (native-inputs (list poetry python-pytest))
-    (home-page "https://flexmock.readthedocs.org")
-    (synopsis "Testing library for Python")
-    (description
-     "flexmock is a testing library for Python that makes it easy to create
-mocks, stubs and fakes.")
-    (license license:bsd-3)))
-
 (define-public python-flaky
   (package
     (name "python-flaky")
diff --git a/gnu/packages/chemistry.scm b/gnu/packages/chemistry.scm
index 06fa6676e23..93fe90a858f 100644
--- a/gnu/packages/chemistry.scm
+++ b/gnu/packages/chemistry.scm
@@ -701,10 +701,20 @@ symmetries written in C.  Spglib can be used to:
        (sha256
         (base32 "0w3c71wvhnc44pfafcjfgqkjimkcdkpjk3bahg9v6l1z8c0cyhfy"))))
     (build-system pyproject-build-system)
+    (arguments
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'unpack 'remove-six
+            (lambda _
+              (substitute* "geometric/nifty.py"
+                (("import six") "")
+                (("six\\.string_types") "str"))
+              (substitute* "setup.py"
+                (("'six',") "")))))))
     (native-inputs
      (list python-pytest
-           python-setuptools
-           python-wheel))
+           python-setuptools))
     (propagated-inputs
      (list python-numpy
            python-scipy
diff --git a/gnu/packages/docker.scm b/gnu/packages/docker.scm
index f2aa2ae9340..e6f4e9c38a8 100644
--- a/gnu/packages/docker.scm
+++ b/gnu/packages/docker.scm
@@ -211,7 +211,7 @@ client.")
            python-docker-5
            python-dockerpty
            python-docopt
-           python-dotenv
+           python-dotenv-0.13.0
            python-jsonschema-3
            python-pyyaml
            python-requests
diff --git a/gnu/packages/efi.scm b/gnu/packages/efi.scm
index 99b41e91693..9a80ca954cd 100644
--- a/gnu/packages/efi.scm
+++ b/gnu/packages/efi.scm
@@ -172,7 +172,7 @@ information.")
     (arguments
      `(#:tests? #f  ; No tests exist.
        #:make-flags
-       '("CC=gcc")
+       '("CC=gcc -g -O2 -Wno-error=implicit-function-declaration")
        #:phases
        (modify-phases %standard-phases
          (add-after 'unpack 'patch
diff --git a/gnu/packages/emacs-xyz.scm b/gnu/packages/emacs-xyz.scm
index 1c10acad067..5343b8147f2 100644
--- a/gnu/packages/emacs-xyz.scm
+++ b/gnu/packages/emacs-xyz.scm
@@ -8455,6 +8455,29 @@ whose goal is to provide colorful yet legible options for users who want
 something with a bit more flair than the Modus themes.")
     (license license:gpl3+)))
 
+(define-public emacs-doric-themes
+  (package
+    (name "emacs-doric-themes")
+    (version "0.4.0")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+              (url "https://github.com/protesilaos/doric-themes")
+              (commit version)))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "06kvv5hvqig1sngzzvpxfpb9wln9fv2b7krjmvb0n3kvp0s0bxmd"))))
+    (build-system emacs-build-system)
+    (arguments (list #:tests? #f))      ;no tests
+    (home-page "https://github.com/protesilaos/doric-themes")
+    (synopsis "Highly readable minimalist Emacs themes")
+    (description
+     "This package provides a set of Emacs themes that conform with a
+minimalist aesthetic: they use few colours and appear monochromatic in many
+contexts")
+    (license license:gpl3+)))
+
 (define-public emacs-eslint-flymake
   (let ((commit "c78246330ee3ac1e0e07a709473d98a113d268e5")
         (revision "1"))
diff --git a/gnu/packages/enlightenment.scm b/gnu/packages/enlightenment.scm
index 8a08262e22d..f0229489570 100644
--- a/gnu/packages/enlightenment.scm
+++ b/gnu/packages/enlightenment.scm
@@ -561,6 +561,7 @@ directories.
 @dfn{Enlightenment Foundation Libraries} (EFL).")
     (license license:bsd-2)))
 
+;; XXX: See: <https://codeberg.org/guix/guix/issues/3014>.
 (define-public epour
   (package
     (name "epour")
@@ -583,8 +584,8 @@ directories.
               (substitute* "epour/gui/__init__.py"
                 (("join\\(data_path")
                  (string-append "join(\"" #$output "/share/epour\""))))))))
-    (native-inputs (list intltool python-distutils-extra python-setuptools
-                         python-wheel))
+    (native-inputs (list intltool python-distutils-extra python-setuptools-67
+                         python-wheel-0.40))
     (inputs (list libtorrent-rasterbar-1.2 python-dbus python-efl python-pyxdg))
     (home-page "https://www.enlightenment.org")
     (synopsis "EFL Bittorrent client")
diff --git a/gnu/packages/esolangs.scm b/gnu/packages/esolangs.scm
index 2f84688f9ad..04f93c6355d 100644
--- a/gnu/packages/esolangs.scm
+++ b/gnu/packages/esolangs.scm
@@ -4,6 +4,7 @@
 ;;; Copyright © 2020 Hendursaga <hendursaga@yahoo.com>
 ;;; Copyright © 2020 Liliana Marie Prikler <liliana.prikler@gmail.com>
 ;;; Copyright © 2022 jgart <jgart@dismail.de>
+;;; Copyright © 2025 Nicolas Graves <ngraves@ngraves.fr>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -26,12 +27,14 @@
   #:use-module (gnu packages flex)
   #:use-module (gnu packages ncurses)
   #:use-module (gnu packages python)
+  #:use-module (gnu packages python-build)
   #:use-module (gnu packages readline)
   #:use-module (guix build-system cmake)
   #:use-module (guix build-system copy)
   #:use-module (guix build-system gnu)
-  #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module (guix download)
+  #:use-module (guix gexp)
   #:use-module (guix git-download)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (guix packages))
@@ -106,18 +109,32 @@ whenever possible to the extent that the above points are not compromised.
     (name "folders")
     (version "0.0.8")
     (source
-      (origin
-        (method url-fetch)
-        (uri (pypi-uri "Folders" version))
-        (sha256
-          (base32 "0qh80qx7sjx0zii1hf8fm853d9rcg4rginm6v4gpp0hgn2a4q4gh"))))
-    (build-system python-build-system)
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/SinaKhalili/Folders.py")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "14fs8c7ilvsw6xbskr688s1dp3nd8vnwv7bg23ab1l6vj6fpzwmw"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (replace 'check
+            (lambda* (#:key tests? #:allow-other-keys)
+              (if tests?
+                  (invoke "Folders" "sample_programs/HelloWorld")
+                  (format #t "test suite not run~%")))))))
+    (native-inputs (list python-setuptools))
     (home-page "https://github.com/SinaKhalili/Folders.py")
     (synopsis "Structural programming language")
-    (description "Folders is a programming language, in which programs
-are encoded as (nested) directories.  Note that the switches you pass to
-@command{du} may affect your score when code golfing.")
-    (properties `((lint-hidden-cpe-vendors . ("premio" "jenkins"))))
+    (description
+     "Folders is a programming language, in which programs are encoded as
+(nested) directories.  Note that the switches you pass to @command{du} may
+affect your score when code golfing.")
+    (properties `((lint-hidden-cpe-vendors "premio" "jenkins")))
     (license license:expat)))
 
 (define-public shakespeare-spl
diff --git a/gnu/packages/finance.scm b/gnu/packages/finance.scm
index 5c51d9329d6..242477f5d4e 100644
--- a/gnu/packages/finance.scm
+++ b/gnu/packages/finance.scm
@@ -799,6 +799,11 @@ other machines/servers.  Electrum does not download the Bitcoin blockchain.")
               (substitute* "electroncash/secp256k1.py"
                 (("libsecp256k1.so.0")
                  (search-input-file inputs "lib/libsecp256k1.so.0")))))
+          (add-after 'unpack 'relax-requirements
+            (lambda _
+              (substitute* "contrib/requirements/requirements.txt"
+                (("python-dateutil<2\\.9")
+                 "python-dateutil"))))
           (add-after 'install 'wrap-qt
             (lambda* (#:key outputs inputs #:allow-other-keys)
               (let ((out (assoc-ref outputs "out")))
diff --git a/gnu/packages/games.scm b/gnu/packages/games.scm
index 738f274324f..f265db356c2 100644
--- a/gnu/packages/games.scm
+++ b/gnu/packages/games.scm
@@ -13408,7 +13408,7 @@ virtual reality devices.")
      (list
       #:configure-flags
       #~(list "-DUSE_TESTS=ON" "-DOPENGL_BACKEND=OpenGL")))
-    (native-inputs (list python-3.10 glibc-locales googletest))
+    (native-inputs (list python glibc-locales googletest))
     (inputs (list freetype
                   libiconv
                   libpng
diff --git a/gnu/packages/gcal.scm b/gnu/packages/gcal.scm
index 32d3849faaa..c9ac90055bd 100644
--- a/gnu/packages/gcal.scm
+++ b/gnu/packages/gcal.scm
@@ -1,5 +1,6 @@
 ;;; GNU Guix --- Functional package management for GNU
 ;;; Copyright © 2013, 2018 Ludovic Courtès <ludo@gnu.org>
+;;; Copyright © 2025 Andy Tai <atai@atai.org>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -20,19 +21,22 @@
   #:use-module (guix packages)
   #:use-module (guix download)
   #:use-module (guix build-system gnu)
-  #:use-module (guix licenses))
+  #:use-module (guix licenses)
+  #:use-module (gnu packages check)
+  #:use-module (gnu packages pkg-config))
+
 
 (define-public gcal
   (package
     (name "gcal")
-    (version "4.1")
+    (version "4.2.0")
     (source (origin
              (method url-fetch)
-             (uri (string-append "mirror://gnu/gcal/gcal-"
+             (uri (string-append "https://www.alteholz.dev/gnu/gcal-"
                                  version ".tar.xz"))
              (sha256
               (base32
-               "1av11zkfirbixn05hyq4xvilin0ncddfjqzc4zd9pviyp506rdci"))
+               "1p3q6his31bxs24nsgpfavw3nlhalqf0zak4f3b530p725s2vgfq"))
              (modules '((guix build utils)))
              (snippet
               '(begin
@@ -50,6 +54,8 @@
                                    "/* BSD stdio derived implementations")))
                  #t))))
     (build-system gnu-build-system)
+    (native-inputs (list check pkg-config))
+    (arguments `(#:configure-flags '("LDFLAGS=-lm")))
     (home-page "https://www.gnu.org/software/gcal/")
     (synopsis "Calculating and printing a wide variety of calendars")
     (description
diff --git a/gnu/packages/genealogy.scm b/gnu/packages/genealogy.scm
index 668505a71a9..f244b5db6c9 100644
--- a/gnu/packages/genealogy.scm
+++ b/gnu/packages/genealogy.scm
@@ -18,9 +18,10 @@
 ;;; along with GNU Guix.  If not, see <http://www.gnu.org/licenses/>.
 
 (define-module (gnu packages genealogy)
-  #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module (guix git-download)
   #:use-module ((guix licenses) #:prefix license:)
+  #:use-module (guix gexp)
   #:use-module (guix packages)
   #:use-module (gnu packages base)
   #:use-module (gnu packages bash)
@@ -34,6 +35,7 @@
   #:use-module (gnu packages graphviz)
   #:use-module (gnu packages gtk)
   #:use-module (gnu packages python)
+  #:use-module (gnu packages python-build)
   #:use-module (gnu packages python-xyz)
   #:use-module (gnu packages sqlite)
   #:use-module (gnu packages version-control)
@@ -52,11 +54,48 @@
        (file-name (git-file-name name version))
        (sha256
         (base32 "1gzhi5hxpgc6pxs40xsxf67hndjifnfhm89s3ly68c70x83qmwhd"))))
-    (build-system python-build-system)
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+      #:imported-modules
+      `((guix build glib-or-gtk-build-system)
+        ,@%pyproject-build-system-modules)
+      #:modules
+      `((ice-9 match)
+        (srfi srfi-1)
+        (guix build pyproject-build-system)
+        ((guix build glib-or-gtk-build-system) #:prefix glib-or-gtk:)
+        (guix build utils))
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'check 'prepare-tests
+            (lambda _
+              (setenv "HOME" (getenv "TMPDIR"))
+              ;; Presence of .git directory is used to determine whether this
+              ;; is a final installation.  Without it, tests fail to determine
+              ;; resource path.
+              (mkdir ".git")
+              ;; Test is failing
+              (delete-file "gramps/gen/utils/test/file_test.py")))
+          (add-before 'wrap 'wrap-with-GI_TYPELIB_PATH
+            (lambda* (#:key inputs #:allow-other-keys)
+              (wrap-program (string-append #$output "/bin/gramps")
+                `("GI_TYPELIB_PATH" ":" prefix
+                  ,(filter-map
+                    (match-lambda
+                      ((output . directory)
+                       (let ((girepodir (string-append
+                                         directory
+                                         "/lib/girepository-1.0")))
+                         (and (file-exists? girepodir)
+                              girepodir))))
+                    inputs)))))
+          (add-after 'wrap 'glib-or-gtk-wrap
+            (assoc-ref glib-or-gtk:%standard-phases 'glib-or-gtk-wrap)))))
     (native-inputs
-     `(("gettext" ,gettext-minimal)
-       ("intltool" ,intltool)
-       ("glibc-utf8-locales" ,glibc-utf8-locales))) ;; for one test
+     (list gettext-minimal intltool
+           glibc-utf8-locales ;for one test
+           python-setuptools))
     (inputs
      (list bash-minimal
            cairo
@@ -81,42 +120,6 @@
            rcs
            sqlite
            xdg-utils))
-    (arguments
-     `(#:imported-modules ((guix build glib-or-gtk-build-system)
-                           ,@%python-build-system-modules)
-       #:modules ((ice-9 match)
-                  (guix build python-build-system)
-                  ((guix build glib-or-gtk-build-system) #:prefix glib-or-gtk:)
-                  (guix build utils))
-       #:phases
-       (modify-phases %standard-phases
-         (add-before 'check 'set-home-for-tests
-           (lambda _
-             (setenv "HOME" (getenv "TMPDIR"))))
-         (add-before 'check 'prepare-tests
-           (lambda _
-             ;; Presence of .git directory is used to determine whether this
-             ;; is a final installation.  Without it, tests fail to determine
-             ;; resource path.
-             (mkdir ".git")
-             ;; Test is failing
-             (delete-file "gramps/gen/utils/test/file_test.py")))
-         (add-before 'wrap 'wrap-with-GI_TYPELIB_PATH
-           (lambda* (#:key inputs outputs #:allow-other-keys)
-             (let ((out (assoc-ref outputs "out"))
-                   (paths (map (match-lambda
-                                 ((output . directory)
-                                  (let ((girepodir (string-append
-                                                    directory
-                                                    "/lib/girepository-1.0")))
-                                    (if (file-exists? girepodir)
-                                        girepodir
-                                        #f))))
-                               inputs)))
-               (wrap-program (string-append out "/bin/gramps")
-                 `("GI_TYPELIB_PATH" ":" prefix ,(filter identity paths))))))
-         (add-after 'wrap 'glib-or-gtk-wrap
-           (assoc-ref glib-or-gtk:%standard-phases 'glib-or-gtk-wrap)))))
     (home-page "https://gramps-project.org")
     (synopsis "Genealogical research software")
     (description
diff --git a/gnu/packages/guile-xyz.scm b/gnu/packages/guile-xyz.scm
index b5b6a3b887b..ad45984a064 100644
--- a/gnu/packages/guile-xyz.scm
+++ b/gnu/packages/guile-xyz.scm
@@ -1189,7 +1189,20 @@ is not available for Guile 2.0.")
               (base32
                "15ynxr3pfjscd6mz641zagv6i84jh9y65i5dnbb3j3q72j6bbvnb"))
              (patches '())))
-    (arguments '())))
+    (arguments
+     (if (target-aarch64?)
+         (list #:phases
+               #~(modify-phases %standard-phases
+                   (add-before 'check 'disable-jit
+                     (lambda _
+                       ;; XXX: Due to a JIT bug in Guile 3.0.9 on AArch64,
+                       ;; some tests would hang:
+                       ;; <https://codeberg.org/fibers/fibers/issues/83>.
+                       ;; Disable JIT for now; re-enable it when Guile 3.0.10+
+                       ;; is used.  (Note: The Shepherd disables JIT on
+                       ;; AArch64 so it can safely use Fibers.)
+                       (setenv "GUILE_JIT_THRESHOLD" "-1")))))
+         '()))))
 
 (define-public guile-fibers guile-fibers-1.4)
 
diff --git a/gnu/packages/guile.scm b/gnu/packages/guile.scm
index 773e3423f23..87a1649970b 100644
--- a/gnu/packages/guile.scm
+++ b/gnu/packages/guile.scm
@@ -502,7 +502,7 @@ without requiring the source code to be rewritten.")
                 ;; The main goal here is to allow for '--with-branch'.
                 (method git-fetch)
                 (uri (git-reference
-                      (url "https://git.savannah.gnu.org/git/guile.git")
+                      (url "https://codeberg.org/guile/guile.git")
                       (commit commit)))
                 (file-name (git-file-name name version))
                 (sha256
diff --git a/gnu/packages/iso-codes.scm b/gnu/packages/iso-codes.scm
index ad9b90a5641..000ea057b30 100644
--- a/gnu/packages/iso-codes.scm
+++ b/gnu/packages/iso-codes.scm
@@ -21,11 +21,11 @@
 
 (define-module (gnu packages iso-codes)
   #:use-module ((guix licenses) #:prefix license:)
+  #:use-module (guix gexp)
   #:use-module (guix packages)
   #:use-module (guix download)
   #:use-module (guix git-download)
   #:use-module (guix build-system gnu)
-  #:use-module (guix build-system python)
   #:use-module (guix build-system pyproject)
   #:use-module (gnu packages check)
   #:use-module (gnu packages gettext)
@@ -152,17 +152,42 @@ region, WIOD classification, ccTLD.")
     (version "0.4.5")
     (source
      (origin
-       (method url-fetch)
-       (uri (pypi-uri "iso-639" version))
+       (method git-fetch)
+       (uri (git-reference
+              (url "https://github.com/noumar/iso639")
+              (commit version)))
+       (file-name (git-file-name name version))
        (sha256
-        (base32
-         "0jffmh4m20q8j27xb2fqbnlghjj0cx8pgsbzqisdg65qh2wd976w"))))
-    (build-system python-build-system)
+        (base32 "02kx6kr3x43linxqafjlx85zdk04s6ab2fv5ikyglghwr5hsvic4"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+      #:test-flags
+      #~(list "tests/tests.py"
+              "-k" (string-join
+                    (list
+                     ;; module 'collections' has no attribute 'Iterable'
+                     "not test_iter"
+                     ;; 'Moroccan Arabic' != 'Arabic'
+                     "test_logic_part2"
+                     ;; 'Languages' object has no attribute 'indices'
+                     "test_compare_alpha2"
+                     "test_compare_bibliographic"
+                     "test_compare_terminology")
+                    " and not "))
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'check 'configure-tests
+            (lambda _
+              (setenv "PYTHONPATH"
+                      (string-append (getcwd) ":"
+                                     (getenv "GUIX_PYTHONPATH"))))))))
+    (native-inputs (list python-pycountry python-pytest python-setuptools))
     (home-page "https://github.com/noumar/iso639")
     (synopsis "Python library for ISO 639 standard")
-    (description "This package provides a Python library for ISO 639 standard
-that is concerned with representation of names for languages and language
-groups.")
+    (description
+     "This package provides a Python library for ISO 639 standard that is
+concerned with representation of names for languages and language groups.")
     (license license:agpl3+)))
 
 (define-public python-iso3166
@@ -171,13 +196,64 @@ groups.")
     (version "2.1.1")
     (source
      (origin
-       (method url-fetch)
-       (uri (pypi-uri "iso3166" version))
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/deactivated/python-iso3166")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
        (sha256
-        (base32
-         "068p94gavc8gbmp5a2kw8hi5l551wfzbpmp6z7ll8sx6vnw53mgw"))))
-    (build-system python-build-system)
+        (base32 "0j0bnm4bd23cyb7dga00gb20myg9skylchkw4d23yh31b7a315m8"))))
+    (build-system pyproject-build-system)
+    (native-inputs (list python-pytest python-setuptools))
     (home-page "https://github.com/deactivated/python-iso3166")
     (synopsis "Self-contained ISO 3166-1 country definitions")
     (description "This package provides the ISO 3166-1 country definitions.")
     (license license:expat)))
+
+(define-public python-pycountry
+  (package
+    (name "python-pycountry")
+    (version "24.6.1")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/pycountry/pycountry")
+             (commit version)))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "0qs99acz1vsj96s8pcwbnp3z3s01mzzvdayk7fm0nnl6lf3lz1g1"))))
+    (build-system pyproject-build-system)
+    (native-inputs (list python-poetry-core python-pytest python-pytest-cov))
+    (home-page "https://github.com/pycountry/pycountry")
+    (synopsis "ISO databases for languages, countries, currencies, etc.")
+    (description
+     "@code{pycountry} provides the ISO databases for the standards:
+     @enumerate
+     @item 639-3 (Languages)
+     @item 3166 (Countries)
+     @item 3166-3 (Deleted Countries)
+     @item 3166-2 (Subdivisions of countries)
+     @item 4217 (Currencies)
+     @item 15924 (Scripts)
+     @end enumerate
+     It includes a copy from Debian’s pkg-isocodes and makes the data accessible
+     through a Python API.")
+    (license license:lgpl2.1+)))
+
+(define-public python-pycountry-20.7.3
+  (hidden-package
+   (package
+     (inherit python-pycountry)
+     (name "python-pycountry")
+     (version "20.7.3")
+     (source
+      (origin
+        (method git-fetch)
+        (uri (git-reference
+               (url "https://github.com/pycountry/pycountry")
+               (commit version)))
+        (file-name (git-file-name name version))
+        (sha256
+         (base32 "1aqzbdqvy3pg0x33ay099vriazs28v6kw7fwc8ajg3avdcws2mgm"))))
+     (native-inputs (list python-pytest python-pytest-cov python-setuptools)))))
diff --git a/gnu/packages/kde-frameworks.scm b/gnu/packages/kde-frameworks.scm
index 4d70a9b276d..e1ccfdcb818 100644
--- a/gnu/packages/kde-frameworks.scm
+++ b/gnu/packages/kde-frameworks.scm
@@ -77,7 +77,6 @@
   #:use-module (gnu packages libcanberra)
   #:use-module (gnu packages linux)
   #:use-module (gnu packages mp3)
-  #:use-module (gnu packages openbox)
   #:use-module (gnu packages pdf)
   #:use-module (gnu packages pcre)
   #:use-module (gnu packages perl)
@@ -96,6 +95,7 @@
   #:use-module (gnu packages video)
   #:use-module (gnu packages vulkan)
   #:use-module (gnu packages web)
+  #:use-module (gnu packages wm)
   #:use-module (gnu packages xml)
   #:use-module (gnu packages xdisorg)
   #:use-module (gnu packages xorg)
diff --git a/gnu/packages/lean.scm b/gnu/packages/lean.scm
index 82bca77dd71..8229c7e7306 100644
--- a/gnu/packages/lean.scm
+++ b/gnu/packages/lean.scm
@@ -24,11 +24,12 @@
   #:use-module (ice-9 match)
   #:use-module (gnu packages base)
   #:use-module (gnu packages bash)
+  #:use-module (gnu packages check)
   #:use-module (gnu packages llvm)
   #:use-module (gnu packages maths)
   #:use-module (gnu packages multiprecision)
   #:use-module (guix build-system cmake)
-  #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (guix gexp)
   #:use-module (guix packages)
@@ -165,18 +166,33 @@ interactive and automated theorem proving.")
   (package
     (name "python-mathlibtools")
     (version "1.1.1")
-    (source (origin
-              (method url-fetch)
-              (uri (pypi-uri "mathlibtools" version))
-              (sha256
-               (base32
-                "089pql105imx8z7ar1wiz9fn000jp6xqdfixw4jf2vric94vn9fj"))))
-    (build-system python-build-system)
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/leanprover-community/mathlib-tools")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "1kllk99cd9vsbmb0ifi21gkhrg2w803z4y5xhx0a7hx3viyjb3cv"))))
+    (build-system pyproject-build-system)
     (arguments
-     '(#:phases (modify-phases %standard-phases
-                  (add-before 'check 'fix-home-directory
-                    (lambda _
-                      (setenv "HOME" "/tmp"))))))
+     (list
+      #:test-flags
+      #~(list "-k"
+              ;; These tests require network access.
+              (string-join (list "not test_new"
+                                 "test_add"
+                                 "test_upgrade_project"
+                                 "test_upgrade_mathlib"
+                                 "test_get_tutorials")
+                           " and not "))
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'check 'fix-home-directory
+            (lambda _
+              (setenv "HOME" "/tmp"))))))
+    (native-inputs (list python-pytest python-setuptools))
     (inputs (list python-toml
                   python-pygithub
                   python-certifi
diff --git a/gnu/packages/libcanberra.scm b/gnu/packages/libcanberra.scm
index cf38ac113e9..52616572fae 100644
--- a/gnu/packages/libcanberra.scm
+++ b/gnu/packages/libcanberra.scm
@@ -26,7 +26,7 @@
   #:use-module (guix packages)
   #:use-module (guix download)
   #:use-module (guix build-system gnu)
-  #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module (gnu packages autotools)
   #:use-module (gnu packages gstreamer)
   #:use-module (gnu packages gtk)
@@ -34,6 +34,7 @@
   #:use-module (gnu packages linux)
   #:use-module (gnu packages pulseaudio)
   #:use-module (gnu packages pkg-config)
+  #:use-module (gnu packages python-build)
   #:use-module (gnu packages xiph))
 
 (define-public libcanberra
@@ -133,15 +134,13 @@ sounds for various system events.")
        (uri (string-append "http://ftp.n0.is/pub/releases/"
                            "pycanberra-" version ".tar.xz"))
        (sha256
-        (base32
-         "16jjf8fcgaprmz6jacsxrh17l1ad891fns38bxv49lg3s3mn1nj2"))))
-    (build-system python-build-system)
-    (arguments
-     `(#:tests? #f)) ;No tests included.
-    (propagated-inputs
-     (list libcanberra))
+        (base32 "16jjf8fcgaprmz6jacsxrh17l1ad891fns38bxv49lg3s3mn1nj2"))))
+    (build-system pyproject-build-system)
+    (arguments (list #:tests? #f))      ;No tests included.
+    (native-inputs (list python-setuptools))
+    (propagated-inputs (list libcanberra))
+    (home-page "https://github.com/totdb/pycanberra")
     (synopsis "Ctypes wrapper for the libcanberra API")
     (description
      "Pycanberra is a basic Python wrapper for libcanberra.")
-    (home-page "http://c.n0.is/ng0/pycanberra/")
     (license lgpl2.1+)))
diff --git a/gnu/packages/lxde.scm b/gnu/packages/lxde.scm
index ba1c1374ef0..3aeb2a5321a 100644
--- a/gnu/packages/lxde.scm
+++ b/gnu/packages/lxde.scm
@@ -47,7 +47,6 @@
   #:use-module (gnu packages libusb)
   #:use-module (gnu packages linux)
   #:use-module (gnu packages lsof)
-  #:use-module (gnu packages openbox)
   #:use-module (gnu packages photo)
   #:use-module (gnu packages pkg-config)
   #:use-module (gnu packages polkit)
diff --git a/gnu/packages/lxqt.scm b/gnu/packages/lxqt.scm
index 634a2f58492..03ec37101a5 100644
--- a/gnu/packages/lxqt.scm
+++ b/gnu/packages/lxqt.scm
@@ -57,7 +57,6 @@
   #:use-module (gnu packages perl)
   #:use-module (gnu packages lxde)
   #:use-module (gnu packages maths)
-  #:use-module (gnu packages openbox)
   #:use-module (gnu packages pcre)
   #:use-module (gnu packages photo)
   #:use-module (gnu packages pkg-config)
@@ -65,6 +64,7 @@
   #:use-module (gnu packages pulseaudio)
   #:use-module (gnu packages qt)
   #:use-module (gnu packages textutils)
+  #:use-module (gnu packages wm)
   #:use-module (gnu packages xdisorg)
   #:use-module (gnu packages xml)
   #:use-module (gnu packages xorg))
diff --git a/gnu/packages/machine-learning.scm b/gnu/packages/machine-learning.scm
index e04525b3d6d..8e8b4c9d088 100644
--- a/gnu/packages/machine-learning.scm
+++ b/gnu/packages/machine-learning.scm
@@ -6121,12 +6121,14 @@ simple speech recognition.")
       (build-system pyproject-build-system)
       (arguments
        (list
+        #:test-backend #~'custom
+        #:test-flags #~(list "../../tests/from_words_to_digits.py")
         #:phases
         #~(modify-phases %standard-phases
             (add-after 'unpack 'chdir
               (lambda _
                 (chdir "package/python"))))))
-      (native-inputs (list python-setuptools python-wheel))
+      (native-inputs (list python-setuptools))
       (propagated-inputs (list python-vosk))
       (home-page "https://github.com/ideasman42/nerd-dictation")
       (synopsis "Offline speech-to-text for desktop Linux")
diff --git a/gnu/packages/mail.scm b/gnu/packages/mail.scm
index fba7b9e08d0..a0d32ff2656 100644
--- a/gnu/packages/mail.scm
+++ b/gnu/packages/mail.scm
@@ -4353,16 +4353,16 @@ It is a replacement for the @command{urlview} program.")
 (define-public mumi
   (package
     (name "mumi")
-    (version "0.13.0")
+    (version "0.14.0")
     (source (origin
               (method git-fetch)
               (uri (git-reference
-                    (url "https://git.savannah.gnu.org/git/guix/mumi.git/")
+                    (url "https://codeberg.org/guix/mumi.git")
                     (commit version)))
               (file-name (git-file-name name version))
               (sha256
                (base32
-                "04mcd1xkdpvxlvpf4k4mvnwi06sdy8vy1di6gxxsr9msgdb366ir"))))
+                "1v5gjzh8idz926518c0bv0qsmyggr6lvqn5vksf5j0qdh6r6dar7"))))
     (build-system gnu-build-system)
     (arguments
      (list
@@ -4743,11 +4743,15 @@ the RFC 8617 Authenticated Received Chain (ARC) protocol.")
          (base32
           "12hl93336w64iyqalpv4rma2ijigav68qy1xmgziibdi7inxr3hi"))))
     (build-system pyproject-build-system)
+    (arguments
+     (list
+      ;; dns.resolver.NoResolverConfiguration: cannot open /etc/resolv.conf
+      #:test-flags #~(list "-k" "not test_authenticate_dmarc_psdsub")))
     (propagated-inputs
      (list python-authres python-dkimpy python-dnspython
            python-publicsuffix2))
     (native-inputs
-     (list python-setuptools python-wheel))
+     (list python-pytest python-setuptools))
     (home-page "https://github.com/ValiMail/authentication-headers")
     (synopsis "Library wrapping email authentication header verification and generation")
     (description
@@ -4760,38 +4764,40 @@ DKIM and ARC sign messages and output the corresponding signature headers.")
     (license (list license:zpl2.1 license:zlib license:mpl2.0))))
 
 (define-public python-aiosmtpd
-  (package
-    (name "python-aiosmtpd")
-    (version "1.4.6")
-    (source
-     (origin
-       (method git-fetch)
-       (uri (git-reference
-             (url "https://github.com/aio-libs/aiosmtpd")
-             (commit (string-append "v" version))))
-       (sha256
-        (base32 "0b5y94zc8pq75sjwsifblzgjnliyclkwypi68b2zffrxcdnz27r2"))
-       (file-name (git-file-name name version))))
-    (build-system pyproject-build-system)
-    (arguments
-     ;; This QA test requires git.
-     (list #:test-flags ''("-k" "not test_ge_master")))
-    (native-inputs
-     (list python-pytest
-           python-pytest-asyncio
-           python-pytest-cov
-           python-pytest-mock
-           python-setuptools
-           python-wheel))
-    (propagated-inputs
-     (list python-atpublic))
-    (home-page "https://aiosmtpd.readthedocs.io/")
-    (synopsis "Asyncio based SMTP server")
-    (description
-     "This project is a reimplementation of the Python stdlib @code{smtpd.py}
+  ;; Tests run fixed on not yet released version.
+  (let ((commit "98f578389ae86e5345cc343fa4e5a17b21d9c96d")
+        (revision "0"))
+    (package
+      (name "python-aiosmtpd")
+      (version (git-version "1.4.6" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+                (url "https://github.com/aio-libs/aiosmtpd")
+                (commit commit)))
+         (sha256
+          (base32 "1pmvlzxfcqjplvn2bzi9jd3m3941ff7nlgxxfwc7pzhmazlkqf8z"))
+         (file-name (git-file-name name version))))
+      (build-system pyproject-build-system)
+      (arguments
+       ;; This QA test requires git.
+       (list #:test-flags ''("-k" "not test_ge_master")))
+      (native-inputs
+       (list python-pytest
+             python-pytest-cov
+             python-pytest-mock
+             python-setuptools))
+      (propagated-inputs
+       (list python-atpublic
+             python-attrs))
+      (home-page "https://aiosmtpd.readthedocs.io/")
+      (synopsis "Asyncio based SMTP server")
+      (description
+       "This project is a reimplementation of the Python stdlib @code{smtpd.py}
 based on asyncio.")
-    (license (list license:asl2.0
-                   license:lgpl3))))    ; only for setup_helpers.py
+      (license (list license:asl2.0
+                     license:lgpl3)))))    ; only for setup_helpers.py
 
 (define-public python-imaplib2
   (package
diff --git a/gnu/packages/maths.scm b/gnu/packages/maths.scm
index 1cd0865263a..82d878592ac 100644
--- a/gnu/packages/maths.scm
+++ b/gnu/packages/maths.scm
@@ -11316,8 +11316,12 @@ the Wolfram language.")
        (sha256
         (base32 "1iagdic8f0yjx01kdds40jfcxcpdbrd3i0ywydl01dhyyvd2yjk9"))))
     (build-system pyproject-build-system)
-    (propagated-inputs (list python-mathics-scanner python-pygments))
-    (native-inputs (list python-setuptools python-wheel))
+    (native-inputs
+     (list python-pytest
+           python-setuptools))
+    (propagated-inputs
+     (list python-mathics-scanner
+           python-pygments))
     (home-page "http://github.com/Mathics3/mathics-pygments/")
     (synopsis "Wolfram language lexer for Pygments")
     (description "This package provides a Wolfram language lexer for Pygments.")
diff --git a/gnu/packages/medical.scm b/gnu/packages/medical.scm
index a9cffacdd9b..8c32731d899 100644
--- a/gnu/packages/medical.scm
+++ b/gnu/packages/medical.scm
@@ -65,28 +65,32 @@
   (package
     (name "mygnuhealth")
     (version "2.2.1")
-    (source (origin
-              (method url-fetch)
-              (uri (pypi-uri "MyGNUHealth" version))
-              (sha256
-               (base32
-                "1jcrriccqzb4jx7zayhiqmpvi3cvfy3bbf9zr3m83878f94yww8j"))))
-    (build-system python-build-system)
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "MyGNUHealth" version))
+       (sha256
+        (base32 "1jcrriccqzb4jx7zayhiqmpvi3cvfy3bbf9zr3m83878f94yww8j"))))
+    (build-system pyproject-build-system)
     (arguments
      (list
-      #:imported-modules `(,@%python-build-system-modules
-                           ,@%qt-build-system-modules)
-      #:modules `(((guix build qt-build-system) #:prefix qt:)
-                  (guix build python-build-system)
-                  (guix build utils))
-      #:phases #~(modify-phases %standard-phases
-                   (add-after 'install 'qt-wrap
-                     (assoc-ref qt:%standard-phases 'qt-wrap))
-                   (add-before 'check 'env-setup
-                     (lambda _
-                       (mkdir-p "/tmp/mygh/")
-                       (setenv "HOME" "/tmp"))))))
-    (native-inputs (list python-pyside-2))
+      #:tests? #f                       ; no tests.
+      #:imported-modules
+      `(,@%pyproject-build-system-modules
+        ,@%qt-build-system-modules)
+      #:modules
+      `(((guix build qt-build-system) #:prefix qt:)
+        (guix build pyproject-build-system)
+        (guix build utils))
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'install 'qt-wrap
+            (assoc-ref qt:%standard-phases 'qt-wrap))
+          (add-before 'check 'env-setup
+            (lambda _
+              (mkdir-p "/tmp/mygh/")
+              (setenv "HOME" "/tmp"))))))
+    (native-inputs (list python-pyside-2 python-setuptools))
     (inputs (list bash-minimal
                   kirigami-5
                   python
diff --git a/gnu/packages/messaging.scm b/gnu/packages/messaging.scm
index 26ea6d55fe7..1b9d6d2cbde 100644
--- a/gnu/packages/messaging.scm
+++ b/gnu/packages/messaging.scm
@@ -3611,21 +3611,24 @@ for notification of events.")
     (license license:gpl3+)))
 
 (define-public python-harmony
+  ;; TODO: Remove python-harmony? Repository is archived.
   (package
     (name "python-harmony")
-    (version "0.7.1")
+    (version "0.7.2")
     (source (origin
               (method git-fetch)
               (uri (git-reference
-                     (url "https://github.com/taylordotfish/harmony.git")
+                     (url "https://github.com/taylordotfish/harmony")
                      (commit version)))
-              (file-name (string-append name "-" version "-checkout"))
+              (file-name (git-file-name name version))
               (sha256
                (base32
-                "1bm9xcnzpnpj6rlhbrnl2abwclzl7ivgh1vb5644y9mnhcs489js"))))
-    (build-system python-build-system)
+                "1d202pymabzvkzmxpplyjv55x74g937abxmnxdg9bxjjvp85c1nv"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list #:tests? #f)) ;no tests in repository
     (native-inputs
-     (list python-tox))
+     (list python-setuptools))
     (inputs
      (list python-librecaptcha python-keyring python-requests))
     (synopsis "Discord account management")
diff --git a/gnu/packages/mpi.scm b/gnu/packages/mpi.scm
index 30d0eac330d..ea5cc62b396 100644
--- a/gnu/packages/mpi.scm
+++ b/gnu/packages/mpi.scm
@@ -36,7 +36,7 @@
   #:use-module (guix deprecation)
   #:use-module (guix build-system cmake)
   #:use-module (guix build-system gnu)
-  #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module (gnu packages)
   #:use-module (gnu packages base)
   #:use-module (gnu packages bash)
@@ -62,6 +62,8 @@
   #:use-module (gnu packages parallel)
   #:use-module (gnu packages pkg-config)
   #:use-module (gnu packages python)
+  #:use-module (gnu packages python-build)
+  #:use-module (gnu packages python-xyz)
   #:use-module (gnu packages ssh)
   #:use-module (gnu packages valgrind)
   #:use-module (gnu packages version-control)
@@ -528,36 +530,48 @@ only provides @code{MPI_THREAD_FUNNELED}.")))
 (define-public python-mpi4py
   (package
     (name "python-mpi4py")
-    (version "3.1.4")
+    (version "4.1.0")
     (source
      (origin
-       (method url-fetch)
-       (uri (pypi-uri "mpi4py" version))
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/mpi4py/mpi4py")
+             (commit version)))
+       (file-name (git-file-name name version))
        (sha256
-        (base32 "101lz7bnm9l17nrkbg6497kxscyh53aah7qd2b820ck2php8z18p"))))
-    (build-system python-build-system)
+        (base32 "1r4n2d3nacpa6sq18jp0xk4a81ha0iipgvlsdv0bhfmdvgpv2vqy"))))
+    (build-system pyproject-build-system)
     (arguments
-     `(#:phases
-       (modify-phases %standard-phases
-         (add-after 'build 'mpi-setup
-           ,%openmpi-setup)
-         (add-before 'check 'pre-check
-           (lambda _
-             ;; Skip BaseTestSpawn class (causes error 'ompi_dpm_dyn_init()
-             ;; failed --> Returned "Unreachable"' in chroot environment).
-             (substitute* "test/test_spawn.py"
-               (("unittest.skipMPI\\('openmpi\\(<3.0.0\\)'\\)")
-                "unittest.skipMPI('openmpi')"))
-             #t)))))
-    (inputs
-     (list openmpi))
-    (properties
-     '((updater-extra-inputs . ("openmpi"))))
+     (list
+      #:test-flags
+      #~(list ;; MPI errors are unrecoverable.
+         "--ignore=test/test_spawn.py"
+         "--ignore=test/test_util_pool.py"
+         "--ignore=demo/futures/test_futures.py")
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'build 'mpi-setup #$%openmpi-setup)
+          (add-before 'check 'pre-check
+            (lambda _
+              ;; Skip BaseTestSpawn class (causes error 'ompi_dpm_dyn_init()
+              ;; failed --> Returned "Unreachable"' in chroot environment).
+              (substitute* "test/test_spawn.py"
+                (("unittest.skipMPI\\('openmpi\\(<3.0.0\\)'\\)")
+                 "unittest.skipMPI('openmpi')"))))
+          (replace 'check
+            (lambda* (#:key tests? test-flags #:allow-other-keys)
+              (if tests?
+                  (apply invoke "mpiexec" "pytest" "-vv" test-flags)
+                  (format #t "test suite not run~%")))))))
+    (native-inputs (list python-cython python-pytest python-setuptools))
+    (inputs (list openmpi))
+    (properties '((updater-extra-inputs "openmpi")))
     (home-page "https://github.com/mpi4py/mpi4py")
     (synopsis "Python bindings for the Message Passing Interface standard")
-    (description "MPI for Python (mpi4py) provides bindings of the Message
-Passing Interface (MPI) standard for the Python programming language, allowing
-any Python program to exploit multiple processors.
+    (description
+     "MPI for Python (mpi4py) provides bindings of the Message Passing
+Interface (MPI) standard for the Python programming language, allowing any
+Python program to exploit multiple processors.
 
 mpi4py is constructed on top of the MPI-1/MPI-2 specification and provides an
 object oriented interface which closely follows MPI-2 C++ bindings.  It
diff --git a/gnu/packages/music.scm b/gnu/packages/music.scm
index 5e7b7015a05..763c21b7933 100644
--- a/gnu/packages/music.scm
+++ b/gnu/packages/music.scm
@@ -154,6 +154,7 @@
   #:use-module (gnu packages image)
   #:use-module (gnu packages image-viewers)
   #:use-module (gnu packages imagemagick)
+  #:use-module (gnu packages iso-codes)
   #:use-module (gnu packages java)
   #:use-module (gnu packages kde-frameworks)
   #:use-module (gnu packages libevent)
@@ -4206,8 +4207,8 @@ websites such as Libre.fm.")
     (license license:asl2.0)))
 
 (define-public instantmusic
-  (let ((commit "300891d09c703525215fa5a116b9294af1c923c8")
-        (revision "1"))
+  (let ((commit "0477dd310e0aeb11d4d113bb96baa40d824cc330")
+        (revision "2"))
     (package
       (name "instantmusic")
       (version (git-version "1.0" revision commit))
@@ -4219,10 +4220,11 @@ websites such as Libre.fm.")
                 (file-name (git-file-name name version))
                 (sha256
                  (base32
-                  "0j7qivaa04bpdz3anmgci5833dgiyfqqwq9fdrpl9m68b34gl773"))))
+                  "0pxp1h0q4j7bidgdh4wgrvnm4ckdr4bvgk1wccr02mynfsjq8x5c"))))
     (build-system pyproject-build-system)
     (arguments
      (list
+      #:tests? #f ;no tests
       #:phases
       #~(modify-phases %standard-phases
           (add-before 'build 'change-directory
@@ -4243,7 +4245,7 @@ websites such as Libre.fm.")
                           (chmod file #o644))
                         (find-files "instantmusic.egg-info"
                                     "PKG-INFO|.*\\.txt")))))))
-    (native-inputs (list python-setuptools python-wheel))
+    (native-inputs (list python-setuptools))
     (inputs (list yt-dlp))
     (propagated-inputs (list python-requests eyed3 python-beautifulsoup4))
     (home-page "https://github.com/yask123/Instant-Music-Downloader")
diff --git a/gnu/packages/nicotine.scm b/gnu/packages/nicotine.scm
index ff6676c4a1d..56c6b6a3116 100644
--- a/gnu/packages/nicotine.scm
+++ b/gnu/packages/nicotine.scm
@@ -23,7 +23,7 @@
   #:use-module (guix packages)
   #:use-module (guix gexp)
   #:use-module (guix git-download)
-  #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module (gnu packages bash)
   #:use-module (gnu packages freedesktop)
   #:use-module (gnu packages glib)
@@ -31,6 +31,7 @@
   #:use-module (gnu packages gettext)
   #:use-module (gnu packages gtk)
   #:use-module (gnu packages mp3)
+  #:use-module (gnu packages python-build)
   #:use-module (gnu packages xorg))
 
 (define-public nicotine+
@@ -45,43 +46,42 @@
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "0xj7hlhgirgjyfmdchksvwhjhaqaf5n84brzih6fqlbsrr9gxkw9"))
-       (modules '((guix build utils)))
-       ;; Remove test that relies on network access.
-       (snippet '(delete-file-recursively
-                  "pynicotine/tests/unit/test_version.py"))))
-    (build-system python-build-system)
+        (base32 "0xj7hlhgirgjyfmdchksvwhjhaqaf5n84brzih6fqlbsrr9gxkw9"))))
+    (build-system pyproject-build-system)
     (arguments
      (list
-      #:imported-modules `((guix build glib-or-gtk-build-system)
-                           ,@%python-build-system-modules)
-      #:modules `((guix build utils)
-                  (guix build python-build-system)
-                  ((guix build glib-or-gtk-build-system)
-                   #:prefix glib-or-gtk:))
-      #:phases #~(modify-phases %standard-phases
-                   (add-after 'install 'wrap-program
-                     (lambda _
-                       (wrap-program (string-append #$output "/bin/nicotine")
-                         `("GI_TYPELIB_PATH" ":" prefix
-                           (,(getenv "GI_TYPELIB_PATH"))))))
-                   (add-after 'wrap-program 'glib-or-gtk-wrap
-                     (assoc-ref glib-or-gtk:%standard-phases
-                                'glib-or-gtk-wrap))
-                   (add-after 'glib-or-gtk-wrap 'glib-or-gtk-compile-schemas
-                     (assoc-ref glib-or-gtk:%standard-phases
-                                'glib-or-gtk-compile-schemas))
-                   (replace 'check
-                     (lambda* (#:key tests? #:allow-other-keys)
-                       (when tests?
-                         (invoke "xvfb-run" "python" "-m" "unittest")))))))
+      #:imported-modules
+      `((guix build glib-or-gtk-build-system)
+        ,@%pyproject-build-system-modules)
+      #:modules
+      `((guix build utils)
+        (guix build pyproject-build-system)
+        ((guix build glib-or-gtk-build-system) #:prefix glib-or-gtk:))
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'install 'wrap-program
+            (lambda _
+              (wrap-program (string-append #$output "/bin/nicotine")
+                `("GI_TYPELIB_PATH" ":" prefix
+                  (,(getenv "GI_TYPELIB_PATH"))))))
+          (add-after 'wrap-program 'glib-or-gtk-wrap
+            (assoc-ref glib-or-gtk:%standard-phases 'glib-or-gtk-wrap))
+          (add-after 'glib-or-gtk-wrap 'glib-or-gtk-compile-schemas
+            (assoc-ref glib-or-gtk:%standard-phases
+                       'glib-or-gtk-compile-schemas))
+          (replace 'check
+            (lambda* (#:key tests? #:allow-other-keys)
+              (when tests?
+                ;; Remove test that relies on network access.
+                (delete-file "pynicotine/tests/unit/test_version.py")
+                (invoke "xvfb-run" "python" "-m" "unittest")))))))
     (inputs (list bash-minimal
                   gspell
                   gtk
                   python-pygobject
                   libappindicator
                   python-pytaglib))
-    (native-inputs (list gettext-minimal xvfb-run))
+    (native-inputs (list gettext-minimal python-setuptools xvfb-run))
     (home-page "https://nicotine-plus.org/")
     (synopsis "Graphical client for Soulseek")
     (description
diff --git a/gnu/packages/ocaml.scm b/gnu/packages/ocaml.scm
index a8410be78b7..8e9fe03a41e 100644
--- a/gnu/packages/ocaml.scm
+++ b/gnu/packages/ocaml.scm
@@ -1470,14 +1470,15 @@ Knuth’s LR(1) parser construction technique.")
                       (wrap-program (string-append #$output "/bin/" "binsec")
                                     `("OCAMLPATH" ":" prefix ,ocamlpath))))))))
     (inputs (list bash-minimal))
-    (native-inputs (list gmp ocaml-qcheck ocaml-ounit2))
+    (native-inputs (list gmp ocaml-qcheck ocaml-ounit2 z3))
     (propagated-inputs (list dune-site
                              ocaml-base
                              ocaml-menhir
                              ocaml-graph
                              ocaml-zarith
                              ocaml-grain-dypgen
-                             ocaml-toml))
+                             ocaml-toml
+                             ocaml-z3))
     (synopsis "Binary-level analysis platform")
     (description
      "BINSEC is a binary analysis platform which implements analysis
diff --git a/gnu/packages/openbox.scm b/gnu/packages/openbox.scm
deleted file mode 100644
index 08ce89b5476..00000000000
--- a/gnu/packages/openbox.scm
+++ /dev/null
@@ -1,120 +0,0 @@
-;;; GNU Guix --- Functional package management for GNU
-;;; Copyright © 2014 Julien Lepiller <julien@lepiller.eu>
-;;; Copyright © 2016, 2023 Efraim Flashner <efraim@flashner.co.il>
-;;; Copyright © 2017 Nikita <nikita@n0.is>
-;;; Copyright © 2022 Maxim Cournoyer <maxim@guixotic.coop>
-;;;
-;;; This file is part of GNU Guix.
-;;;
-;;; GNU Guix is free software; you can redistribute it and/or modify it
-;;; under the terms of the GNU General Public License as published by
-;;; the Free Software Foundation; either version 3 of the License, or (at
-;;; your option) any later version.
-;;;
-;;; GNU Guix is distributed in the hope that it will be useful, but
-;;; WITHOUT ANY WARRANTY; without even the implied warranty of
-;;; MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
-;;; GNU General Public License for more details.
-;;;
-;;; You should have received a copy of the GNU General Public License
-;;; along with GNU Guix.  If not, see <http://www.gnu.org/licenses/>.
-
-(define-module (gnu packages openbox)
-  #:use-module ((guix licenses) #:select (gpl2+))
-  #:use-module (guix packages)
-  #:use-module (guix download)
-  #:use-module (guix utils)
-  #:use-module (guix build-system gnu)
-  #:use-module (guix gexp)
-  #:use-module (gnu packages)
-  #:use-module (gnu packages autotools)
-  #:use-module (gnu packages freedesktop)
-  #:use-module (gnu packages gettext)
-  #:use-module (gnu packages gnome)
-  #:use-module (gnu packages gtk)
-  #:use-module (gnu packages image)
-  #:use-module (gnu packages pkg-config)
-  #:use-module (gnu packages python)
-  #:use-module (gnu packages xdisorg)
-  #:use-module (gnu packages xml)
-  #:use-module (gnu packages xorg))
-
-(define-public openbox
-  (package
-    (name "openbox")
-    (version "3.6.1")
-    (source (origin
-              (method url-fetch)
-              (uri (string-append
-                    "http://openbox.org/dist/openbox/" name "-"
-                    version ".tar.xz"))
-              (sha256
-               (base32
-                "0vg2y1qddsdxkjv806mzpvmkgzliab8ll4s7zm7ma5jnriamirxb"))
-              (patches (search-patches "openbox-add-fix-for-glib2-exposed-segfault.patch" "openbox-python3.patch"))))
-    (build-system gnu-build-system)
-    (arguments
-     (list #:phases
-           #~(modify-phases %standard-phases
-               (add-after 'unpack 'force-reconfigure
-                 ;; This is made necessary by the openbox-python3 patch.
-                 (lambda _
-                   (delete-file "configure"))))))
-    (native-inputs (list autoconf automake gettext-minimal libtool pkg-config))
-    (propagated-inputs (list python-pyxdg))
-    (inputs (list imlib2
-                  libxml2
-                  (librsvg-for-system)
-                  libsm
-                  libxcursor
-                  libxinerama
-                  libxml2
-                  libxrandr
-                  libxft
-                  pango
-                  python-wrapper))
-    (synopsis "Box style window manager")
-    (description
-     "Openbox is a highly configurable, next generation window manager with
-extensive standards support.  The *box visual style is well known for its
-minimalistic appearance.  Openbox uses the *box visual style, while providing
-a greater number of options for theme developers than previous *box
-implementations.")
-    (home-page "http://openbox.org/wiki/Main_Page")
-    (license gpl2+)))
-
-(define-public obconf
-  (package
-    (name "obconf")
-    (version "2.0.4")
-    (source
-     (origin
-       (method url-fetch)
-       (uri (string-append "http://openbox.org/dist/" name
-                           "/" name "-" version ".tar.gz"))
-       (sha256
-        (base32
-         "1fanjdmd8727kk74x5404vi8v7s4kpq48l583d12fsi4xvsfb8vi"))))
-    (inputs (list gtk+-2
-                  imlib2
-                  libglade
-                  libsm
-                  librsvg
-                  libxft
-                  openbox
-                  startup-notification))
-    (native-inputs (list gettext-minimal pkg-config))
-    (build-system gnu-build-system)
-    (arguments
-     (list
-       #:configure-flags
-         #~(list "--enable-nls"
-                 "CFLAGS=-g -O2 -Wno-error=implicit-function-declaration")))
-    (home-page "https://openbox.org/obconf")
-    (synopsis "Openbox configuration tool")
-    (description
-     "Obconf is a tool for configuring the Openbox window manager.
-You can configure its appearance, themes, and much more.")
-    (license gpl2+)))
-
-;;; openbox.scm ends here
diff --git a/gnu/packages/package-management.scm b/gnu/packages/package-management.scm
index 4fa251d6294..9b0c4f1857d 100644
--- a/gnu/packages/package-management.scm
+++ b/gnu/packages/package-management.scm
@@ -1931,7 +1931,7 @@ This package just includes the agent component.")))
 (define-public guix-jupyter
   (package
     (name "guix-jupyter")
-    (version "0.3.0")
+    (version "0.3.1")
     (home-page "https://codeberg.org/guix-science/guix-jupyter")
     (source (origin
               (method git-fetch)
@@ -1939,7 +1939,7 @@ This package just includes the agent component.")))
                                   (commit (string-append "v" version))))
               (sha256
                (base32
-                "0cvjxv60la2bqmwb7m2bfpvjy8hx1hmjk2qy9wfzaffcabgr0x44"))
+                "1yvrmaj4qcb9vn2nfjz1q0cil830hvmxpp8cgi76aylbnv36aask"))
               (file-name (string-append "guix-jupyter-" version "-checkout"))))
     (build-system gnu-build-system)
     (arguments
diff --git a/gnu/packages/patchutils.scm b/gnu/packages/patchutils.scm
index 511f8bfead6..540b85b41aa 100644
--- a/gnu/packages/patchutils.scm
+++ b/gnu/packages/patchutils.scm
@@ -35,7 +35,7 @@
   #:use-module (guix build-system glib-or-gtk)
   #:use-module (guix build-system meson)
   #:use-module (guix build-system ocaml)
-  #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module (gnu packages)
   #:use-module (gnu packages autotools)
   #:use-module (gnu packages base)
@@ -367,40 +367,37 @@ you to figure out what is going on in that merge you keep avoiding.")
   (package
     (name "patchwork")
     (version "3.2.1")
-    (source (origin
-              (method git-fetch)
-              (uri (git-reference
-                    (url "https://github.com/getpatchwork/patchwork")
-                    (commit (string-append "v" version))))
-              (file-name (git-file-name name version))
-              (sha256
-               (base32
-                "04ikawdyhjwspxvhazbp5f5vym672y0jcw8rd2m75h9ipcpnyxim"))))
-    (build-system python-build-system)
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/getpatchwork/patchwork")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "04ikawdyhjwspxvhazbp5f5vym672y0jcw8rd2m75h9ipcpnyxim"))))
+    (build-system pyproject-build-system)
     (arguments
-     `(;; TODO: Tests require a running database
-       #:tests? #f
-       #:phases
-       (modify-phases %standard-phases
-         (delete 'configure)
-         (delete 'build)
-         (add-after 'unpack 'replace-wsgi.py
-           (lambda* (#:key inputs outputs #:allow-other-keys)
-             (delete-file "patchwork/wsgi.py")
-             (call-with-output-file "patchwork/wsgi.py"
-               (lambda (port)
-                 ;; Embed the PYTHONPATH containing the dependencies, as well
-                 ;; as the python modules in this package in the wsgi.py file,
-                 ;; as this will ensure they are available at runtime.
-                 (define pythonpath
-                   (string-append (getenv "GUIX_PYTHONPATH")
-                                  ":"
-                                  (site-packages inputs outputs)))
-                 (display
-                  (string-append "
-import os, sys
-
-sys.path.extend('" pythonpath "'.split(':'))
+     (list
+      #:tests? #f ;TODO: Tests require a running database
+      #:phases
+      #~(modify-phases %standard-phases
+          (delete 'configure)
+          (delete 'build)
+          (add-after 'unpack 'replace-wsgi.py
+            (lambda* (#:key inputs outputs #:allow-other-keys)
+              (delete-file "patchwork/wsgi.py")
+              (call-with-output-file "patchwork/wsgi.py"
+                (lambda (port)
+                  ;; Embed the PYTHONPATH containing the dependencies, as well
+                  ;; as the python modules in this package in the wsgi.py file,
+                  ;; as this will ensure they are available at runtime.
+                  (define pythonpath
+                    (string-append (getenv "GUIX_PYTHONPATH") ":"
+                                   (site-packages inputs outputs)))
+                  (display (string-append
+                            "\nimport os, sys\n\nsys.path.extend('" pythonpath
+                            "'.split(':'))
 
 from django.core.wsgi import get_wsgi_application
 
@@ -415,89 +412,88 @@ os.environ['DJANGO_SETTINGS_MODULE'] = os.getenv(
 )
 
 application = get_wsgi_application()\n") port)))))
-         (replace 'check
-           (lambda* (#:key tests? #:allow-other-keys)
-             (when tests?
-               (setenv "DJANGO_SETTINGS_MODULE" "patchwork.settings.dev")
-               (invoke "python" "-Wonce" "./manage.py" "test" "--noinput"))
-             #t))
-         (replace 'install
-           (lambda* (#:key inputs outputs #:allow-other-keys)
-             (let ((out (assoc-ref outputs "out"))
-                   (out-site-packages (site-packages inputs outputs)))
-               (for-each (lambda (directory)
-                           (copy-recursively
-                            directory
-                            (string-append out-site-packages "/" directory)))
-                         '(;; Contains the python code
-                           "patchwork"
-                           ;; Contains the templates for the generated HTML
-                           "templates"))
-               (delete-file-recursively
-                (string-append out-site-packages "/patchwork/tests"))
+          (replace 'check
+            (lambda* (#:key tests? #:allow-other-keys)
+              (when tests?
+                (setenv "DJANGO_SETTINGS_MODULE" "patchwork.settings.dev")
+                (invoke "python" "-Wonce" "./manage.py" "test" "--noinput"))))
+          (replace 'install
+            (lambda* (#:key inputs outputs #:allow-other-keys)
+              (let ((out (assoc-ref outputs "out"))
+                    (out-site-packages (site-packages inputs outputs)))
+                (for-each (lambda (directory)
+                            (copy-recursively directory
+                                              (string-append out-site-packages
+                                               "/" directory)))
+                          '( ;Contains the python code
+                             "patchwork"
+                            ;; Contains the templates for the generated HTML
+                            "templates"))
+                (delete-file-recursively (string-append out-site-packages
+                                                        "/patchwork/tests"))
 
-               ;; Install patchwork related tools
-               (for-each (lambda (file)
-                           (install-file file (string-append out "/bin")))
-                         (list
-                          (string-append out-site-packages
-                                         "/patchwork/bin/parsemail.sh")
-                          (string-append out-site-packages
-                                         "/patchwork/bin/parsemail-batch.sh")))
+                ;; Install patchwork related tools
+                (for-each (lambda (file)
+                            (install-file file
+                                          (string-append out "/bin")))
+                          (list (string-append out-site-packages
+                                               "/patchwork/bin/parsemail.sh")
+                                (string-append out-site-packages
+                                 "/patchwork/bin/parsemail-batch.sh")))
 
-               ;; Collect the static assets, this includes JavaScript, CSS and
-               ;; fonts. This is a standard Django process when running a
-               ;; Django application for regular use, and includes assets for
-               ;; dependencies like the admin site from Django.
-               ;;
-               ;; The intent here is that you can serve files from this
-               ;; directory through a webserver, which is recommended when
-               ;; running Django applications.
-               (let ((static-root
-                      (string-append out "/share/patchwork/htdocs")))
-                 (mkdir-p static-root)
-                 (copy-file "patchwork/settings/production.example.py"
-                            "patchwork/settings/assets.py")
-                 (setenv "DJANGO_SECRET_KEY" "dummyvalue")
-                 (setenv "DJANGO_SETTINGS_MODULE" "patchwork.settings.assets")
-                 (setenv "STATIC_ROOT" static-root)
-                 (invoke "./manage.py" "collectstatic" "--no-input"))
+                ;; Collect the static assets, this includes JavaScript, CSS and
+                ;; fonts. This is a standard Django process when running a
+                ;; Django application for regular use, and includes assets for
+                ;; dependencies like the admin site from Django.
+                ;;
+                ;; The intent here is that you can serve files from this
+                ;; directory through a webserver, which is recommended when
+                ;; running Django applications.
+                (let ((static-root (string-append out
+                                                  "/share/patchwork/htdocs")))
+                  (mkdir-p static-root)
+                  (copy-file "patchwork/settings/production.example.py"
+                             "patchwork/settings/assets.py")
+                  (setenv "DJANGO_SECRET_KEY" "dummyvalue")
+                  (setenv "DJANGO_SETTINGS_MODULE" "patchwork.settings.assets")
+                  (setenv "STATIC_ROOT" static-root)
+                  (invoke "./manage.py" "collectstatic" "--no-input"))
 
-               ;; The lib directory includes example configuration files that
-               ;; may be useful when deploying patchwork.
-               (copy-recursively "lib"
-                                 (string-append
-                                  out "/share/doc/" ,name "-" ,version)))
-             #t))
-         ;; The hasher script is used from the post-receive.hook
-         (add-after 'install 'install-hasher
-           (lambda* (#:key inputs outputs #:allow-other-keys)
-             (let* ((out (assoc-ref outputs "out"))
-                    (out-site-packages (site-packages inputs outputs))
-                    (out-hasher.py (string-append out-site-packages
-                                                  "/patchwork/hasher.py")))
-               (chmod out-hasher.py #o555)
-               (symlink out-hasher.py (string-append out "/bin/hasher")))
-             #t))
-         ;; Create a patchwork specific version of Django's command line admin
-         ;; utility.
-         (add-after 'install 'install-patchwork-admin
-           (lambda* (#:key inputs outputs #:allow-other-keys)
-             (let* ((out (assoc-ref outputs "out")))
-               (mkdir-p (string-append out "/bin"))
-               (call-with-output-file (string-append out "/bin/patchwork-admin")
-                 (lambda (port)
-                   (simple-format port "#!~A
+                ;; The lib directory includes example configuration files that
+                ;; may be useful when deploying patchwork.
+                (copy-recursively "lib"
+                                  (string-append out "/share/doc/"
+                                                 #$name "-"
+                                                 #$version)))))
+          ;; The hasher script is used from the post-receive.hook
+          (add-after 'install 'install-hasher
+            (lambda* (#:key inputs outputs #:allow-other-keys)
+              (let* ((out (assoc-ref outputs "out"))
+                     (out-site-packages (site-packages inputs outputs))
+                     (out-hasher.py (string-append out-site-packages
+                                                   "/patchwork/hasher.py")))
+                (chmod out-hasher.py #o555)
+                (symlink out-hasher.py
+                         (string-append out "/bin/hasher")))))
+          ;; Create a patchwork specific version of Django's command line admin
+          ;; utility.
+          (add-after 'install 'install-patchwork-admin
+            (lambda _
+              (mkdir-p (string-append #$output "/bin"))
+              (call-with-output-file (string-append #$output
+                                                    "/bin/patchwork-admin")
+                (lambda (port)
+                  (simple-format port "#!~A
 import os, sys
 
 if __name__ == \"__main__\":
     from django.core.management import execute_from_command_line
 
     execute_from_command_line(sys.argv)" (which "python"))))
-               (chmod (string-append out "/bin/patchwork-admin") #o555))
-             #t)))))
-    (inputs
-     (list python-wrapper))
+              (chmod (string-append #$output "/bin/patchwork-admin")
+                     #o555))))))
+    (native-inputs (list python-setuptools))
+    (inputs (list python-wrapper))
     (propagated-inputs
      (list python-django
            ;; TODO: Make this configurable
@@ -553,47 +549,34 @@ patches do not match perfectly.")
   (package
     (name "pwclient")
     (version "1.3.0")
-    (source (origin
-              (method git-fetch)
-              (uri (git-reference
-                    (url "https://github.com/getpatchwork/pwclient")
-                    (commit version)))
-              (file-name (git-file-name name version))
-              (sha256
-               (base32
-                "1xckwvcqklzpyh3xs4k2zm40ifp0q5fdkj2vmgb8vhfvl1ivs6jv"))))
-    (build-system python-build-system)
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/getpatchwork/pwclient")
+             (commit version)))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "1xckwvcqklzpyh3xs4k2zm40ifp0q5fdkj2vmgb8vhfvl1ivs6jv"))))
+    (build-system pyproject-build-system)
     (arguments
-     `(#:phases
-       (modify-phases %standard-phases
-         (add-after 'unpack 'patch-requirements
-           (lambda _
-             (substitute* "test-requirements.txt"
-               ;; The pytest requirement is unnecessarily strict
-               (("pytest>=3.0,<5.0;")
-                "pytest>=3.0,<6.0;"))
-             #t))
-         (add-before 'build 'set-PBR_VERSION
-           (lambda _
-             (setenv "PBR_VERSION"
-                     ,version)
-             #t))
-         (replace 'check
-           (lambda* (#:key tests? #:allow-other-keys)
-             (when tests?
-               (invoke "pytest"))
-             #t))
-         (add-after 'install 'install-man-page
-           (lambda* (#:key outputs #:allow-other-keys)
-             (install-file "man/pwclient.1"
-                           (string-append
-                            (assoc-ref outputs "out")
-                            "/share/man/man1"))
-             #t)))))
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'build 'set-PBR_VERSION
+            (lambda _
+              (setenv "PBR_VERSION" #$version)))
+          (add-after 'install 'install-man-page
+            (lambda _
+              (install-file "man/pwclient.1"
+                            (string-append #$output "/share/man/man1")))))))
     (native-inputs
-     (list python-pbr python-pytest python-pytest-cov python-mock))
-    (home-page
-     "https://github.com/getpatchwork/pwclient")
+     (list python-pbr
+           python-pytest
+           python-pytest-cov
+           python-mock
+           python-setuptools))
+    (home-page "https://github.com/getpatchwork/pwclient")
     (synopsis "Command-line client for the Patchwork patch tracking tool")
     (description
      "pwclient is a VCS-agnostic tool for interacting with Patchwork, the
diff --git a/gnu/packages/prolog.scm b/gnu/packages/prolog.scm
index c6d5f42aa5b..6404da5d51b 100644
--- a/gnu/packages/prolog.scm
+++ b/gnu/packages/prolog.scm
@@ -185,7 +185,7 @@ it.")
 (define-public trealla
   (package
     (name "trealla")
-    (version "2.83.8")
+    (version "2.83.11")
     (source
      (origin
        (method git-fetch)
@@ -194,7 +194,7 @@ it.")
          (url "https://github.com/trealla-prolog/trealla")
          (commit (string-append "v" version))))
        (sha256
-        (base32 "1bpfzrwsgbmjl1maiaw5b8ixkgh548gw1lkiznsjgkjm7dxr4ns4"))
+        (base32 "00kbcq9mzxqm3hgfgbxjblb733lzy1hvfwnf73a5gxnfdbqhr5dz"))
        (file-name (git-file-name name version))))
     (build-system gnu-build-system)
     (native-inputs
diff --git a/gnu/packages/python-check.scm b/gnu/packages/python-check.scm
index c95596dd4d6..e40b92f5083 100644
--- a/gnu/packages/python-check.scm
+++ b/gnu/packages/python-check.scm
@@ -1,8 +1,11 @@
 ;;; GNU Guix --- Functional package management for GNU
-;;; Copyright © 2015 Cyril Roelandt <tipecaml@gmail.com>
+;;; Copyright © 2015, 2017 Cyril Roelandt <tipecaml@gmail.com>
 ;;; Copyright © 2015, 2019, 2020, 2021 Efraim Flashner <efraim@flashner.co.il>
 ;;; Copyright © 2016-2022 Marius Bakke <marius@gnu.org>
+;;; Copyright © 2016 宋文武 <iyzsong@envs.net>
 ;;; Copyright © 2017 Muriithi Frederick Muriuki <fredmanglis@gmail.com>
+;;; Copyright © 2017 Thomas Danckaert <thomas.danckaert@gmail.com>
+;;; Copyright © 2018 Fis Trivial <ybbs.daans@hotmail.com>
 ;;; Copyright © 2018-2020 Tobias Geerinckx-Rice <me@tobias.gr>
 ;;; Copyright © 2019-2025 Ricardo Wurmus <rekado@elephly.net>
 ;;; Copyright © 2019-2024 Maxim Cournoyer <maxim@guixotic.coop>
@@ -23,6 +26,7 @@
 ;;; Copyright © 2022 Tomasz Jeneralczyk <tj@schwi.pl>
 ;;; Copyright © 2022 jgart <jgart@dismail.de>
 ;;; Copyright © 2023 John Kehayias <john.kehayias@protonmail.com>
+;;; Copyright © 2024 Danny Milosavljevic <dannym@friendly-machines.com>
 ;;; Copyright © 2024-2025 Troy Figiel <troy@troyfigiel.com>
 ;;; Copyright © 2024 Navid Afkhami <navid.afkhami@mdc-berlin.de>
 ;;; Copyright © 2024, 2025 David Elsing <david.elsing@posteo.net>
@@ -226,6 +230,38 @@ the implementation of that name.")
     (license (list license:asl2.0
                    license:lgpl3))))    ; only for setup_helpers.py
 
+(define-public python-autopep8
+  (package
+    (name "python-autopep8")
+    (version "2.3.2")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "autopep8" version))
+       (sha256
+        (base32 "0n0pjdk39n6vlddjqvbpkxd4a7q33dkf0k2yk6dbd5wijr7hli49"))))
+    (build-system pyproject-build-system)
+    (propagated-inputs
+     (list python-pycodestyle python-tomli))
+    (native-inputs
+     (list python-setuptools))
+    (arguments
+     `(#:phases
+       (modify-phases %standard-phases
+         (add-before 'check 'prepare-check
+           (lambda _
+             (setenv "HOME" "/tmp"))))))
+    (home-page "https://github.com/hhatto/autopep8")
+    (synopsis "Format Python code according to the PEP 8 style guide")
+    (description
+     "@code{autopep8} automatically formats Python code to conform to
+the PEP 8 style guide.  It uses the pycodestyle utility to determine
+what parts of the code needs to be formatted.  @code{autopep8} is
+capable of fixing most of the formatting issues that can be reported
+by pycodestyle.")
+    (license (license:non-copyleft
+              "https://github.com/hhatto/autopep8/blob/master/LICENSE"))))
+
 (define-public python-avocado-framework
   (package
     (name "python-avocado-framework")
@@ -786,6 +822,27 @@ list/set/dict comprehensions.")
 providing hints about what deprecated methods should be replaced with.")
     (license license:gpl2)))
 
+(define-public python-flexmock
+  (package
+    (name "python-flexmock")
+    (version "0.12.2")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "flexmock" version))
+       (sha256
+        (base32 "18dcr7mpldf3cxsqi9rak75n4z7x3j544l4ixdspairm7cf6cp23"))))
+    (build-system pyproject-build-system)
+    (native-inputs
+     (list python-poetry-core
+           python-pytest))
+    (home-page "https://flexmock.readthedocs.io/")
+    (synopsis "Testing library for Python")
+    (description
+     "flexmock is a testing library for Python that makes it easy to create
+mocks, stubs and fakes.")
+    (license license:bsd-3)))
+
 (define-public python-gcovr
   (package
     (name "python-gcovr")
diff --git a/gnu/packages/python-crypto.scm b/gnu/packages/python-crypto.scm
index 32b9f17aaa7..b20bec061fd 100644
--- a/gnu/packages/python-crypto.scm
+++ b/gnu/packages/python-crypto.scm
@@ -1771,6 +1771,7 @@ in different situations.
 @end enumerate")
     (license license:expat)))
 
+;; XXX: Not maintained since 2016.
 (define-public python-pydes
   (package
     (name "python-pydes")
@@ -1782,8 +1783,10 @@ in different situations.
        (sha256
         (base32 "04lh71f47y04vspfrdrq6a0hn060ibxvdp5z1pcr0gmqs8hqxaz2"))))
     (build-system pyproject-build-system)
-    (native-inputs (list python-setuptools python-wheel))
-    (home-page "http://twhiteman.netfirms.com/des.html")
+    (arguments
+     (list #:tests? #f))        ;no tests in PyPI, I could not fine Git
+    (native-inputs (list python-setuptools))
+    (home-page "http://twhiteman.netfirms.com/des.html") ;XXX: Dead link
     (synopsis
      "Pure python implementation of the DES and TRIPLE DES encryption algorithms")
     (description
diff --git a/gnu/packages/python-science.scm b/gnu/packages/python-science.scm
index 7b4c7cdfe5d..ad89a3940ae 100644
--- a/gnu/packages/python-science.scm
+++ b/gnu/packages/python-science.scm
@@ -335,22 +335,34 @@ reduces the code overhead typically encountered when using a mostly
 object-oriented library such as @code{scikit-learn}.")
     (license license:bsd-3)))
 
+;; XXX: See: <https://codeberg.org/guix/guix/issues/3093>.
 (define-public python-aplus
-  (package
-    (name "python-aplus")
-    (version "0.11.0")
-    (source
-     (origin
-       (method url-fetch)
-       (uri (pypi-uri "aplus" version))
-       (sha256
-        (base32 "1rznc26nlp641rn8gpdngfp79a3fji38yavqakxi35mx2da04msg"))))
-    (build-system python-build-system)
-    (home-page "https://github.com/xogeny/aplus")
-    (synopsis "Promises/A+ for Python")
-    (description "This package is an implementation of the Promises/A+
-specification and test suite in Python.")
-    (license license:expat)))
+  ;; PyPI release lacks the latest version, Git has no tags.
+  (let ((commit "1ab8ebec987fb7213766784aad02cbf4410d9036")
+        (revision "0"))
+    (package
+      (name "python-aplus")
+      (version (git-version "0.11.1" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+                (url "https://github.com/xogeny/aplus")
+                (commit commit)))
+         (file-name (git-file-name name version))
+         (sha256
+          (base32 "02jcfj7dywvs0sd60c85pxwh0mwsj9p1q27445pba6j489x3dffj"))))
+      (build-system pyproject-build-system)
+      (arguments
+       (list #:tests? #f))      ;they depend on Nose test runner
+      (native-inputs
+       (list python-setuptools))
+      (home-page "https://github.com/xogeny/aplus")
+      (synopsis "Promises/A+ for Python")
+      (description
+       "This package is an implementation of the Promises/A+ specification and
+test suite in Python.")
+      (license license:expat))))
 
 (define-public python-apted
   ;; PyPI release lacks tests and there is no Git tag.
@@ -3930,19 +3942,25 @@ production-critical data pipelines or reproducible research settings.  With
     ;; marked turtle can be skipped using "-m" "not turtle".
     (arguments
      (list
-      #:test-flags '(list
-                     "-n" (number->string (parallel-job-count))
-                     ;; Tries to connect to the internet.
-                     "-k" (string-append "not test_is_connected"
-                                         ;; Test files are not included
-                                         " and not test_read_commandline_bad_cmd")
-                     ;; Test files are not included
-                     "--ignore=tests/io/test_read_csvs.py"
-                     ;; Polars has not been packaged yet.
-                     "--ignore=tests/polars"
-                     ;; PySpark has not been packaged yet.
-                     "--ignore=tests/spark/functions/test_clean_names_spark.py"
-                     "--ignore=tests/spark/functions/test_update_where_spark.py")
+      ;; tests: 1042 passed, 2 skipped, 2 deselected, 45 xfailed, 6 xpassed,
+      ;;        735 warnings
+      #:test-flags
+      ;; The tests take quite long, so consider adding the "-n" line and
+      ;; adding python-pytest-xdist to the native-inputs when testing.
+      ;; However, the tests are not deterministic when ran with -n, so
+      ;; disable again before committing.
+      #~(list ;; "-n" (number->string (parallel-job-count))
+              ;; Test files are not included.
+              "--ignore=tests/io/test_read_csvs.py"
+              ;; Polars has not been packaged yet.
+              "--ignore=tests/polars"
+              ;; PySpark has not been packaged yet.
+              "--ignore=tests/spark/functions/test_clean_names_spark.py"
+              "--ignore=tests/spark/functions/test_update_where_spark.py"
+              ;; Tries to connect to the internet.
+              "-k" (string-append "not test_is_connected"
+                                  ;; Test files are not included.
+                                  " and not test_read_commandline_bad_cmd"))
       #:phases
       #~(modify-phases %standard-phases
           (add-before 'check 'set-env-ci
@@ -3950,20 +3968,22 @@ production-critical data pipelines or reproducible research settings.  With
               ;; Some tests are skipped if the JANITOR_CI_MACHINE
               ;; variable is not set.
               (setenv "JANITOR_CI_MACHINE" "1"))))))
+    ;; TODO: Remove python-requests and inject its target data to make the
+    ;; package behaviour reproducible.
     (propagated-inputs (list python-multipledispatch
                              python-natsort
                              python-pandas-flavor
+                             python-requests
                              python-scipy
                              ;; Optional imports.
                              python-biopython ;biology submodule
                              python-unyt)) ;engineering submodule
     (native-inputs (list python-pytest
-                         python-pytest-xdist
+                         ;;python-pytest-xdist ;only for -n when testing
+                         python-setuptools
                          ;; Optional imports. We do not propagate them due to
                          ;; their size.
                          python-numba ;speedup of joins
-                         python-setuptools
-                         python-wheel
                          rdkit)) ;chemistry submodule
     (home-page "https://github.com/pyjanitor-devs/pyjanitor")
     (synopsis "Tools for cleaning and transforming pandas DataFrames")
@@ -4123,6 +4143,8 @@ changed, it made sense to abstract away the nuisance of having to re-learn
 them.")
   (license license:bsd-3)))
 
+;; XXX: Not maintained since 2019. The project was archived by the owner on
+;; Nov 2, 2020. It is now read-only.
 (define-public python-fbpca
   (package
     (name "python-fbpca")
@@ -4133,7 +4155,10 @@ them.")
               (sha256
                (base32
                 "1lbjqhqsdmqk86lb86q3ywf7561zmdny1dfvgwqkyrkr4ij7f1hm"))))
-    (build-system python-build-system)
+    (build-system pyproject-build-system)
+    (arguments
+     (list #:test-flags #~(list "fbpca.py")))
+    (native-inputs (list python-pytest python-setuptools))
     (propagated-inputs
      (list python-numpy python-scipy))
     (home-page "https://fbpca.readthedocs.io/")
diff --git a/gnu/packages/python-web.scm b/gnu/packages/python-web.scm
index fe7f39333f1..1200ffb3ad4 100644
--- a/gnu/packages/python-web.scm
+++ b/gnu/packages/python-web.scm
@@ -64,6 +64,8 @@
 ;;; Copyright © 2023 dan <i@dan.games>
 ;;; Copyright © 2023 John Kehayias <john.kehayias@protonmail.com>
 ;;; Copyright © 2023 Ivan Vilata-i-Balaguer <ivan@selidor.net>
+;;; Copyright © 2024 Fabio Natali <me@fabionatali.com>
+;;; Copyright © 2024 Steve George <steve@futurile.net>
 ;;; Copyright © 2024 Troy Figiel <troy@troyfigiel.com>
 ;;; Copyright © 2024, 2025 Sharlatan Hellseher <sharlatanus@gmail.com>
 ;;; Copyright © 2024 normally_js <normally_js@posteo.net>
@@ -120,6 +122,7 @@
   #:use-module (gnu packages gnupg)
   #:use-module (gnu packages graphviz)
   #:use-module (gnu packages groff)
+  #:use-module (gnu packages iso-codes)
   #:use-module (gnu packages libevent)
   #:use-module (gnu packages libffi)
   #:use-module (gnu packages libidn)
@@ -205,6 +208,112 @@ writing applications that talk to network enabled embedded
 @acronym{IoT,Internet of Things} devices.")
     (license license:expat)))
 
+(define-public python-apprise
+  (package
+    (name "python-apprise")
+    (version "1.9.4")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "apprise" version))
+       (sha256
+        (base32 "126951n9lnlqrw5lbsvs9xs7jzg33bqqxm7cfnqag2csw6p24ca8"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+      ;; These tests used to be ran with --numprocesses, but that seems to have
+      ;; made them non-deterministic.
+      #:test-flags
+      #~(list "--ignore=tests/test_plugin_macosx.py"
+              "-k" "not test_plugin_glib_send_raises_generic")))
+    (native-inputs
+     (list python-babel
+           python-pytest
+           python-pytest-mock
+           python-setuptools))
+    (propagated-inputs
+     (list python-certifi
+           python-click
+           python-markdown
+           python-pygobject
+           python-pyyaml
+           python-requests
+           python-requests-oauthlib))
+    (home-page "https://github.com/caronc/apprise")
+    (synopsis "Push notification library")
+    (description
+     "Apprise is a Python library that allows sending push notifications to a
+broad range of notification services, such as Telegram, Discord, Slack, Amazon
+SNS, Gotify, etc.")
+    (license license:bsd-2)))
+
+(define-public python-blacksheep
+  (package
+    (name "python-blacksheep")
+    (version "2.4.0")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+              (url "https://github.com/Neoteroi/BlackSheep")
+              (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "1iwlj6vl0rnvddbn9zsdgpya88z0lifr86wz3ci1d67li7w5bjiq"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+      ;; tests: 1443 passed, 3 skipped
+      ;;
+      ;; 1. Ignore integration tests.
+      ;; 2. Client tests use test fixture no longer available in
+      ;; pytest-asyncio,
+      ;;
+      ;; See: <https://github.com/Neoteroi/BlackSheep/issues/596>.
+      #:test-flags
+      #~(list "--ignore=itests"
+              "--ignore=tests/client")
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'build 'cythonize
+            (lambda _
+              (with-directory-excursion "blacksheep"
+                (for-each (lambda (file)
+                            (invoke "cython" "-3" file "-I" "."))
+                          (find-files "." ".*\\.pyx$"))))))))
+    (native-inputs
+     (list python-cython
+           python-flask
+           python-jinja2
+           python-pydantic
+           python-pyjwt
+           python-pytest
+           python-pytest-asyncio
+           python-setuptools))
+    (propagated-inputs
+     (list python-certifi
+           python-dateutil
+           python-essentials-openapi
+           python-guardpost
+           python-itsdangerous))
+    (home-page "https://github.com/Neoteroi/BlackSheep")
+    (synopsis "Asynchronous framework to build event based web applications")
+    (description
+     "BlackSheep is a lightweight, asynchronous, event driven Web framework.
+
+The framework offers
+@itemize
+@item A rich code API, based on dependency injection and inspired by Flask and
+ASP.NET Core.
+@item A typing-friendly codebase, which enables a comfortable development
+experience thanks to hints when coding with IDEs.
+@item Built-in generation of OpenAPI Documentation, supporting version 3, YAML,
+and JSON.
+@item A cross-platform framework, using the most modern versions of Python.
+@item Good performance.
+@end itemize")
+    (license license:expat)))
+
 (define-public python-devpi-common
   (package
     (name "python-devpi-common")
@@ -606,6 +715,40 @@ Async mode for @url{https://domainconnect.org/, Domain Connect protocol}.")
 Dropbox API v2.")
     (license license:expat)))
 
+(define-public python-essentials-openapi
+  (package
+    (name "python-essentials-openapi")
+    (version "1.2.1")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/Neoteroi/essentials-openapi")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "0f3lhpkqhvv8sr1c34cvzdqkc61306m03w3jp0zdih1v6is05j8x"))))
+    (build-system pyproject-build-system)
+    (native-inputs
+     (list python-flask
+           python-hatchling
+           python-pydantic
+           python-pytest
+           python-rich))
+    (propagated-inputs
+     (list python-essentials
+           python-httpx
+           python-jinja2
+           python-markupsafe
+           python-pyyaml))
+    (home-page "https://github.com/Neoteroi/essentials-openapi/")
+    (synopsis "Generator for OpenAPI Documentation")
+    (description
+     "Generator for OpenAPI Documentation version 2 and 3, in JSON and YAML
+formats.  Generator for other kinds of documents from OpenAPI Documentation
+files.")
+    (license license:expat)))
+
 (define-public python-eventlet
   (package
     (name "python-eventlet")
@@ -773,6 +916,51 @@ formats (PDF/XML/CSV).")
 @url{https://www.globus.org/, Globus} APIs.")
     (license license:asl2.0)))
 
+(define-public python-guardpost
+  (package
+    (name "python-guardpost")
+    (version "1.0.2")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+              (url "https://github.com/Neoteroi/guardpost")
+              (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "1cwxxxhazpaphhcysgpivk51vp76zdf7hrryc1vr6vlp2zzgwsxd"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+      ;; Possible timing issue, see:
+      ;; <https://github.com/Neoteroi/GuardPost/issues/18>.
+      #:test-flags '(list "--ignore=tests/test_jwts.py")))
+    (native-inputs
+     (list python-cryptography
+           python-flask
+           python-hatchling
+           python-pyjwt
+           python-pytest
+           python-pytest-asyncio))
+    (propagated-inputs
+     (list python-rodi))
+    (home-page "https://github.com/Neoteroi/GuardPost/")
+    (synopsis
+     "Authentication and authorization framework for Python applications")
+    (description
+     "GuardPost is a framework to handle authentication and
+authorization in asynchronous Python applications.
+
+Its features include
+
+@itemize
+@item Strategy to implement authentication.
+@item Strategy to implement authorization.
+@item Support for dependency injection
+@item Built-in support for JSON Web Tokens (JWTs) authentication.
+@end itemize")
+    (license license:expat)))
+
 (define-public python-hookdns
   (package
     (name "python-hookdns")
@@ -1699,9 +1887,8 @@ It features a minimal TLS 1.3 implementation, a QUIC stack and an HTTP/3 stack."
       ;; This test opens a remote connection.
       #~(list "-k" "not test_create_connection_resolve_good")))
     (native-inputs (list python-pytest
-                         python-pytest-asyncio
-                         python-setuptools
-                         python-wheel))
+                         python-pytest-asyncio-0.26
+                         python-setuptools))
     (propagated-inputs
      (list python-attrs python-websockets))
     (home-page "https://github.com/kyuupichan/aiorpcX")
@@ -5295,7 +5482,10 @@ WebSocket usage in Python programs.")
        (method url-fetch)
        (uri (pypi-uri "websocket-client" version))
        (sha256
-        (base32 "0p0cz2mdissq7iw1n7jrmsfir0jfmgs1dvnpnrx477ffx9hbsxnk"))))))
+        (base32 "0p0cz2mdissq7iw1n7jrmsfir0jfmgs1dvnpnrx477ffx9hbsxnk"))))
+    (native-inputs
+     (modify-inputs (package-native-inputs python-websocket-client)
+       (append python-six)))))
 
 (define-public python-purl
   (package
@@ -10640,19 +10830,44 @@ can be handled by the @code{colorsys} module in the Python standard library.")
     (license license:bsd-3)))
 
 (define-public python-woob
+  ;; TODO: woob requires backends which are currently installed on the fly in
+  ;; ~/.local/share/woob/modules/3.7/woob_modules/ , perhaps we should install
+  ;; them in the store instead. Many modules are included in the modules
+  ;; directory in the source tree, but it is unclear how to install them.
+  ;; Many modules require extra dependencies though, so maybe they should be
+  ;; packaged independently of woob itself.
   (package
     (name "python-woob")
-    (version "3.0")
+    (version "3.7")
     (source
      (origin
-       (method url-fetch)
-       (uri (pypi-uri "woob" version))
+       (method git-fetch)
+       (uri (git-reference
+              (url "https://gitlab.com/woob/woob.git")
+              (commit version)))
+       (file-name (git-file-name name version))
        (sha256
-        (base32 "09hpxy5zhn2b8li0xjf3zd7s46lawb0315p5mdcsci3bj3s4v1j7"))))
-    (build-system python-build-system)
-    ;; A small number of tests for optional applications fails due to missing
-    ;; inputs.
-    (arguments `(#:tests? #f))
+        (base32 "1sy0aykff56xs4dnc7ak6m8is2zgz9fprf3i1pk8n861xz1z748i"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+      #:test-flags
+      ;; Deselect tests that require DNS lookup.
+      #~(list
+         "--deselect=tests/browser/adapters.py::TestAdapter::test_ciphers"
+         "--deselect=tests/browser/browsers.py::TestBrowser::test_verify")
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'build 'relax-requirements
+            (lambda _
+              ;; "packaging ~= 23.0",
+              (substitute* "pyproject.toml"
+                (("\"packaging .*\",")
+                 "")))))))
+    (native-inputs
+     (list nss-certs-for-test
+           python-pytest
+           python-setuptools))
     (propagated-inputs
      (list python-babel
            python-colorama
@@ -10661,19 +10876,20 @@ can be handled by the @code{colorsys} module in the Python standard library.")
            python-feedparser
            python-html2text
            python-lxml
+           python-packaging
            python-pillow
            python-prettytable
-           python-pyqt
+           python-pycountry
            python-pyyaml
            python-requests
-           python-six
+           python-responses
+           python-rich
+           python-termcolor
            python-unidecode))
-    (native-inputs
-     (list python-coverage python-flake8 python-nose python-selenium
-           python-xunitparser))
     (home-page "https://woob.tech/")
     (synopsis "Woob, Web Outside Of Browsers")
-    (description "Woob is a collection of applications able to interact with
+    (description
+     "Woob is a collection of applications able to interact with
 websites, without requiring the user to open them in a browser.  It also
 provides well-defined APIs to talk to websites lacking one.")
     (license license:lgpl3+)))
diff --git a/gnu/packages/python-xyz.scm b/gnu/packages/python-xyz.scm
index e8e373652f9..30a14303a3d 100644
--- a/gnu/packages/python-xyz.scm
+++ b/gnu/packages/python-xyz.scm
@@ -237,6 +237,7 @@
   #:use-module (gnu packages image-processing)
   #:use-module (gnu packages imagemagick)
   #:use-module (gnu packages inkscape)
+  #:use-module (gnu packages iso-codes)
   #:use-module (gnu packages java)
   #:use-module (gnu packages jupyter)
   #:use-module (gnu packages kerberos)
@@ -344,46 +345,6 @@ protocol of git-annex, while leaving the behavior of the remote up to the
 user.")
     (license license:gpl3)))
 
-(define-public python-apprise
-  (package
-    (name "python-apprise")
-    (version "1.9.3")
-    (source
-     (origin
-       (method url-fetch)
-       (uri (pypi-uri "apprise" version))
-       (sha256
-        (base32 "19k51ici58134m61f6di0m36mbqgdyr6r31i8v6rk22vldz6d0zm"))))
-    (build-system pyproject-build-system)
-    (arguments
-     (list
-      #:test-flags
-      #~(list "--numprocesses" (number->string (parallel-job-count))
-              "--ignore=test/test_plugin_macosx.py"
-              ;; AssertionError
-              "--deselect=test/test_plugin_wxpusher.py::test_plugin_wxpusher_urls")))
-    (native-inputs
-     (list python-babel
-           python-pytest
-           python-pytest-mock
-           python-pytest-xdist
-           python-setuptools
-           python-wheel))
-    (propagated-inputs
-     (list python-certifi
-           python-click
-           python-markdown
-           python-pyyaml
-           python-requests
-           python-requests-oauthlib))
-    (home-page "https://github.com/caronc/apprise")
-    (synopsis "Push notification library")
-    (description
-     "Apprise is a Python library that allows sending push notifications to a
-broad range of notification services, such as Telegram, Discord, Slack, Amazon
-SNS, Gotify, etc.")
-    (license license:bsd-2)))
-
 (define-public python-archspec
   (package
     (name "python-archspec")
@@ -646,7 +607,8 @@ line drawing algorithm}.")
        (sha256
         (base32 "08dmi4chamk5dbdpvrc0nb09iybfhj3wqwxgffiqnkj7030qhqb8"))))
     (build-system pyproject-build-system)
-    (native-inputs (list python-setuptools python-wheel))
+    ;; tests: 797 passed, 1 warning
+    (native-inputs (list python-pytest python-setuptools))
     (propagated-inputs (list python-ply))
     (home-page "https://github.com/calmjs/calmjs.parse/")
     (synopsis "Parsers for ECMA standards")
@@ -1015,6 +977,8 @@ package. ")
 It also supports IPython/Jupyter.")
     (license license:expat)))
 
+;; TODO: Move to ci or task-runners, see:
+;; <https://codeberg.org/guix/guix/issues/3096>.
 (define-public python-huey
   (package
     (name "python-huey")
@@ -1038,9 +1002,12 @@ It also supports IPython/Jupyter.")
               (substitute* "huey/tests/test_kt_huey.py"
                 (("^has_ktserver = sp.call\\(\\['which', 'ktserver'\\].*$")
                  "has_ktserver = False"))))
-          (add-before 'check 'pre-check
-            (lambda _ (spawn "redis-server" '("redis-server")))))))
-    (native-inputs (list python-setuptools python-wheel redis tzdata-for-tests))
+          (replace 'check
+            (lambda* (#:key tests? #:allow-other-keys)
+              (when tests?
+                (spawn "redis-server" '("redis-server"))
+                (invoke "python3" "-m" "runtests" "--verbosity" "2")))))))
+    (native-inputs (list python-setuptools redis tzdata-for-tests))
     (propagated-inputs (list python-redis))
     (home-page "https://huey.readthedocs.io")
     (synopsis "Lightweight task queue for Python")
@@ -4179,7 +4146,7 @@ with Numpy and SciPy.")
 (define-public python-rich-tables
   (package
     (name "python-rich-tables")
-    (version "0.6.1")
+    (version "0.8.0")
     (source
      (origin
        (method git-fetch)   ; no tests data in PyPi package
@@ -4188,8 +4155,13 @@ with Numpy and SciPy.")
              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "1wqr6sldf97ycs4gfvsqhbh1ki2kgsaicsy44g9lspvlda5nfcp1"))))
+        (base32 "1gkwgxcjnghn0alqw53kgb4ixf047dnb49kc0af3blvcwnmfmb5f"))))
     (build-system pyproject-build-system)
+    (arguments
+     (list
+      #:test-flags
+      ;; TypeError: can't subtract offset-naive and offset-aware datetimes
+      #~(list "--deselect=tests/test_outputs.py::test_outputs[tests/json/album.json]")))
     (native-inputs
      (list python-freezegun
            python-poetry-core
@@ -4197,6 +4169,7 @@ with Numpy and SciPy.")
            python-pytest-cov))
     (propagated-inputs
      (list python-funcy
+           python-humanize
            python-multimethod
            python-platformdirs
            python-rgbxy
@@ -4809,6 +4782,31 @@ Unicode-to-LaTeX conversion.")
 @code{subprocess} feature.")
     (license license:expat)))
 
+;; Old version just for python-dotenv-0.13.0 for docker-compose; remove once
+;; that is updated.
+(define-public python-sh-1
+  (package
+    (inherit python-sh)
+    (version "1.14.2")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "sh" version))
+       (sha256
+        (base32
+         "03gyss1rhj4in7pgysg4q0hxp3230whinlpy1532ljs99lrx0ywx"))))
+    ;(build-system python-build-system)
+    (arguments
+     '(#:phases
+       (modify-phases %standard-phases
+         (replace 'check
+           (lambda _
+             ;; XXX: A Python 2 test fails when HOME=/homeless-shelter.
+             (setenv "HOME" "/tmp")
+             (invoke "python" "sh.py" "test"))))))
+    (native-inputs
+     (list python-setuptools))))
+
 (define-public python-cftime
   (package
     (name "python-cftime")
@@ -6499,9 +6497,11 @@ other Python program.")
                (base32
                 "0skrs5i5pvpzvihgxw766zi1c9bbp33aisdldxgj470mlchvdgyy"))))
     (build-system pyproject-build-system)
+    (arguments
+     (list #:test-backend #~'custom
+           #:test-flags #~(list "tests/functional/tests.py")))
     (native-inputs
-     (list python-setuptools
-           python-wheel))
+     (list python-setuptools))
     (home-page "https://agateau.com/projects/doxyqml")
     (synopsis "Doxygen input filter for QML files")
     (description
@@ -7753,6 +7753,7 @@ something else) to Python data-types.")
         (base32
          "10zqvpaky51kgb8nd42bk7jwl8cn2zvayxjpdc1wwmpybj92x67s"))))))
 
+;; XXX: See: <https://codeberg.org/guix/guix/issues/3029>.
 (define-public python-kconfiglib
   (package
     (name "python-kconfiglib")
@@ -7764,9 +7765,10 @@ something else) to Python data-types.")
        (sha256
         (base32 "0g690bk789hsry34y4ahvly5c8w8imca90ss4njfqf7m2qicrlmy"))))
     (build-system pyproject-build-system)
+    (arguments
+     (list #:tests? #f)) ;tests require complex set up
     (native-inputs
      (list python-setuptools
-           python-wheel
            `(,python "tk")))
     (home-page "https://github.com/ulfalizer/Kconfiglib")
     (synopsis
@@ -8518,6 +8520,7 @@ important tasks for becoming a daemon process:
     ;; Only setup.py is gpl3+, everything else is apache 2.0 licensed.
     (license (list license:asl2.0 license:gpl3+))))
 
+;; XXX: See: <https://codeberg.org/guix/guix/issues/3027>.
 (define-public python-elevate
   (package
     (name "python-elevate")
@@ -8530,13 +8533,14 @@ important tasks for becoming a daemon process:
         (base32 "02g23lxzzl64j1b4fsnrdxqiahl9lnrqyxpqwcfzn0g33px1kbak"))))
     (build-system pyproject-build-system)
     (arguments
-     `(#:phases
+     `(#:tests? #f ;no tests in PyPI
+       #:phases
        (modify-phases %standard-phases
          (add-after 'unpack 'clean-up
            (lambda _
              ;; Uses stuff we don't have.
              (delete-file "elevate/windows.py"))))))
-    (native-inputs (list python-setuptools python-wheel))
+    (native-inputs (list python-setuptools))
     (home-page "https://github.com/barneygale/elevate")
     (synopsis "Python library for requesting root privileges")
     (description "This package provides a Python library for requesting
@@ -12292,39 +12296,6 @@ run simple @code{argparse} parsers from function signatures.")
 from a program in a @dfn{pager} such as @command{less}.")
     (license license:asl2.0)))
 
-(define-public python-autopep8
-  (package
-    (name "python-autopep8")
-    (version "2.0.4")
-    (source
-     (origin
-       (method url-fetch)
-       (uri (pypi-uri "autopep8" version))
-       (sha256
-        (base32
-         "037yhzmc9lssmn6cifa5gvw23f1c0hgsfgn83jfl3cwppm50c4r9"))))
-    (build-system pyproject-build-system)
-    (propagated-inputs
-     (list python-pycodestyle python-tomli))
-    (native-inputs
-     (list python-setuptools python-wheel))
-    (arguments
-     `(#:phases
-       (modify-phases %standard-phases
-         (add-before 'check 'prepare-check
-           (lambda _
-             (setenv "HOME" "/tmp"))))))
-    (home-page "https://github.com/hhatto/autopep8")
-    (synopsis "Format Python code according to the PEP 8 style guide")
-    (description
-     "@code{autopep8} automatically formats Python code to conform to
-the PEP 8 style guide.  It uses the pycodestyle utility to determine
-what parts of the code needs to be formatted.  @code{autopep8} is
-capable of fixing most of the formatting issues that can be reported
-by pycodestyle.")
-    (license (license:non-copyleft
-              "https://github.com/hhatto/autopep8/blob/master/LICENSE"))))
-
 (define-public python-dirty-equals
   (package
     (name "python-dirty-equals")
@@ -13745,10 +13716,10 @@ memoizing PEG/Packrat parser in Python.")
 (define-public python-grandalf
   (package
     (name "python-grandalf")
-    (version "0.7")
+    ;; `guix refresh` will try to upgrade to v0.55555, but that is older.
+    (version "0.8")
     (source
      (origin
-       ;; There's no source tarball on PyPI.
        (method git-fetch)
        (uri (git-reference
              (url "https://github.com/bdcht/grandalf")
@@ -13756,16 +13727,18 @@ memoizing PEG/Packrat parser in Python.")
        (file-name (git-file-name name version))
        (sha256
         (base32
-         "03p8w8ljpb87qbyldm3s6b7qi30hfcn43h33iwlgqcf31fjsyr4g"))))
-    (build-system python-build-system)
+         "199f86hz3g4p237ma4j27rzwmska3bxzsbgq20i4l4pczf9v7ax0"))))
+    (build-system pyproject-build-system)
     (arguments
-     '(#:phases
-       (modify-phases %standard-phases
-         (replace 'check
-           (lambda _
-             (invoke "python" "setup.py" "pytest"))))))
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'build 'patch-requirements
+            (lambda _
+              (substitute* "setup.py"
+                (("install_requires=\\['pyparsing'],") "")))))))
     (native-inputs
-     (list python-pytest python-pytest-runner))
+     (list python-setuptools python-pytest))
     (propagated-inputs
      (list python-numpy python-ply))
     (home-page "https://github.com/bdcht/grandalf")
@@ -17279,7 +17252,7 @@ pseudo terminal (pty), and interact with both the process and its pty.")
        ;; XXX: Snippet below is required because on v1.1.30 the source code
        ;; has configshell_fb as softlink to configshell and guix
        ;; pyproject-build-system doesn't work with symlinks very well.
-       ;; 
+       ;;
        ;; This package is only used in spdk for now and it's crucial to keep
        ;; it locked on version and keep the snipped for spdk to build
        ;; successfully.
@@ -20156,18 +20129,22 @@ and dataclasses.")
 (define-public python-argparse-manpage
   (package
     (name "python-argparse-manpage")
-    (version "4.5")
+    (version "4.7")
     (source
      (origin
        (method url-fetch)
-       (uri (pypi-uri "argparse-manpage" version))
+       (uri (pypi-uri "argparse_manpage" version))
        (sha256
-        (base32
-         "1nq4sq1zk1xzdsqq61hd27jhj978ys136aba1zjg02x1g0c0cg11"))))
+        (base32 "0clb20scp408gxac675v731vnj89pk9d5fb7pcy7bj1a45mvgshx"))))
     (build-system pyproject-build-system)
+    (arguments
+     (list
+      #:test-flags
+      ;; Tests require PIP.
+      #~(list "--ignore=tests/test_examples.py")))
     (native-inputs
-     (list python-pip python-pytest python-setuptools python-tomli
-           python-wheel))
+     (list python-pytest
+           python-setuptools))
     (home-page "https://github.com/praiskup/argparse-manpage")
     (synopsis "Build manual page from Python's ArgumentParser object")
     (description
@@ -20367,6 +20344,33 @@ package and greatly reduce the number of imports for your users.  It is a small
 pure Python module that works on virtually all Python versions.")
     (license license:expat)))
 
+(define-public python-essentials
+  (package
+    (name "python-essentials")
+    (version "1.1.6")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/Neoteroi/essentials")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "1bh8yi79gn9fg26mp58nm9xhnxcfab7rhc076av4qg00mg5p9rn0"))))
+    (build-system pyproject-build-system)
+    (native-inputs
+     (list python-hatchling
+           python-pydantic
+           python-pytest-asyncio))
+    (home-page "https://github.com/Neoteroi/essentials/wiki")
+    (synopsis
+     "Utility functions, exceptions, and classes for Python applications")
+    (description
+     "Essentials is a collection of functions, exceptions, and classes for Python
+applications.  Examples of utilities are exceptions for common scenarios,
+friendly JSON encoder, decorators for retries and logging.")
+    (license license:expat)))
+
 (define-public python-execnet
     (package
       (name "python-execnet")
@@ -23191,7 +23195,7 @@ specified in POSIX.1-2001 and POSIX.1-2008.")
        (sha256
         (base32 "1clb3lfw694crq8m767q0yjaazkplcrbzdr9fr2w39hhndivhcd6"))))
     (build-system pyproject-build-system)
-    (native-inputs (list python-setuptools python-wheel))
+    (native-inputs (list python-pytest python-setuptools))
     (home-page "https://github.com/rocky/pycolumnize")
     (synopsis "Format a simple (i.e. not nested) list into aligned columns.")
     (description
@@ -25286,6 +25290,41 @@ GraphQL schema describes your data model, and provides a GraphQL server with
 an associated set of resolve methods that know how to fetch data.")
     (license license:expat)))
 
+(define-public python-rodi
+  (package
+    (name "python-rodi")
+    (version "2.0.8")
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/Neoteroi/rodi")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "0kf98yjllrq7vqcp07r2gmkqcviqglsnai3sdigdsrwrfc0b44yp"))))
+    (build-system pyproject-build-system)
+    (native-inputs
+     (list python-hatchling
+           python-pytest
+           python-pytest-asyncio))
+    (home-page "https://github.com/Neoteroi/rodi")
+    (synopsis "Dependency injection framework for Python")
+    (description
+     "Rodi is a dependency injection framework for Python applications.
+
+Its features include
+
+@itemize
+@item Type resolution by signature types annotations.
+@item Type resolution by class annotations.
+@item Type resolution by names and aliases.
+@item Build graph of objects without the need for source code changes.
+@item Minimum overhead to obtain services, once the objects graph is built.
+@item Support for singleton, transient, and scoped services.
+@end itemize")
+    (license license:expat)))
+
 ;; XXX: The last time updated in 2015, consider to remove it when nothing is
 ;; depend on it.
 (define-public python-snowballstemmer
@@ -25990,46 +26029,6 @@ converting text with ANSI color codes to HTML or LaTeX.")
      can even create animations with the cursor controls.")
     (license license:expat)))
 
-(define-public python-pycountry
-  (package
-    (name "python-pycountry")
-    (version "22.3.5")
-    (source
-     (origin
-       (method url-fetch)
-       (uri (pypi-uri "pycountry" version))
-       (sha256
-        (base32
-         "0ihnkh86zz01vi46gcwgq6h71jrpj7hq71zi13c98n2qdhj3l5mj"))))
-    (build-system python-build-system)
-    (home-page "https://bitbucket.org/flyingcircus/pycountry")
-    (synopsis "ISO databases for languages, countries, currencies, etc.")
-    (description
-     "@code{pycountry} provides the ISO databases for the standards:
-     @enumerate
-     @item 639-3 (Languages)
-     @item 3166 (Countries)
-     @item 3166-3 (Deleted Countries)
-     @item 3166-2 (Subdivisions of countries)
-     @item 4217 (Currencies)
-     @item 15924 (Scripts)
-     @end enumerate
-     It includes a copy from Debian’s pkg-isocodes and makes the data accessible
-     through a Python API.")
-    (license license:lgpl2.1+)))
-
-(define-public python-pycountry@20.7.3
-  (package
-    (inherit python-pycountry)
-    (name "python-pycountry")
-    (version "20.7.3")
-    (source
-     (origin
-       (method url-fetch)
-       (uri (pypi-uri "pycountry" version))
-       (sha256
-        (base32 "0hnbabsmqimx5hqh0jbd2f64i8fhzhhbrvid57048hs5sd9ll241"))))))
-
 (define-public python-pycosat
   (package
     (name "python-pycosat")
@@ -26967,9 +26966,10 @@ filetypes can be easily added by creating plugins for them.")
        (sha256
         (base32 "0c3dgm1rf7ih79pgkj7adffn8hlyqh5qah8rbzlq436kz3srk83q"))))
     (build-system pyproject-build-system)
+    (arguments
+     (list #:tests? #f)) ;no tests in PyPI or Git
     (native-inputs
-     (list python-setuptools
-           python-wheel))
+     (list python-setuptools))
     (home-page "https://github.com/benknight/hue-python-rgb-converter")
     (synopsis "RGB conversion tool in Python")
     (description
@@ -29437,29 +29437,32 @@ supports the globstar @code{**} operator to match an arbitrary number of
 path components.")
     (license license:asl2.0)))
 
+;; XXX: Not maintained since 2021.
 (define-public python-git-hammer
   (package
     (name "python-git-hammer")
-    (version "0.3.1")
+    (version "0.3.2")
     (source
      (origin
        (method git-fetch)
        (uri (git-reference
-             (url "https://github.com/asharov/git-hammer")
-             (commit version)))
+              (url "https://github.com/asharov/git-hammer")
+              (commit version)))
        (file-name (git-file-name name version))
        (sha256
-        (base32
-         "0f9xlk86ijzpdj25hr1q4wcy8k72v3w470ngwm9mpdkfj8ng84wr"))))
-    (build-system python-build-system)
+        (base32 "0j0skpbhi7js45hp1w2n87093yz1hjdg5y3kicwvm84fb8i38gvx"))))
+    (build-system pyproject-build-system)
     (arguments
-     `(#:phases
-       (modify-phases %standard-phases
-         (add-after 'unpack 'patch-setup.py
+     (list
+      #:phases
+      #~(modify-phases %standard-phases
+         (add-after 'unpack 'relax-requirements
            (lambda _
              (substitute* "setup.py"
-               (("setup\\(")
-                "setup(\n    test_suite=\"test\",")))))))
+               (("matplotlib <3.1") "matplotlib")))))))
+    (native-inputs
+     (list python-pytest
+           python-setuptools))
     (propagated-inputs
      (list python-beautifultable
            python-dateutil
@@ -29471,8 +29474,8 @@ path components.")
     (home-page "https://github.com/asharov/git-hammer")
     (synopsis "Provide statistics for git repositories")
     (description
-     "Git Hammer is a statistics tool for projects in git repositories.
-Its major feature is tracking the number of lines authored by each person for every
+     "Git Hammer is a statistics tool for projects in git repositories. Its major
+feature is tracking the number of lines authored by each person for every
 commit, but it also includes some other useful statistics.")
     (license license:asl2.0)))
 
@@ -30962,6 +30965,7 @@ module.")
     (properties '((upstream-name . "Wikidata")))
     (license license:gpl3+)))
 
+;; XXX: Not maintained since 2022, leaf package.
 (define-public python-attr
   (package
     (name "python-attr")
@@ -30973,8 +30977,11 @@ module.")
        (sha256
         (base32 "1x2627x0n2rxx8wib4cksbjjnncff8finq97k37dq70qd2kvrvhw"))))
     (build-system pyproject-build-system)
+    (arguments
+     (list #:test-backend #~'custom
+           #:test-flags #~(list "-c" "import dry_attr; dry_attr.test()")))
     (native-inputs
-     (list python-setuptools python-wheel))
+     (list python-setuptools))
     (home-page "https://github.com/denis-ryzhkov/attr")
     (synopsis "Decorator for attributes of target function or class")
     (description "Simple decorator to set attributes of target function or
@@ -32109,6 +32116,7 @@ register custom encoders and decoders.")
 bindings for Python 3.")
     (license license:bsd-3)))
 
+;; XXX: See: <https://codeberg.org/guix/guix/issues/3054>.
 (define-public python-iocapture
   ;; The latest release is more than a year older than this commit.
   (let ((commit "fdc021c431d0840303908dfc3ca8769db383595c")
@@ -32126,8 +32134,12 @@ bindings for Python 3.")
          (sha256
           (base32 "1mkbhqibxvgwg0p7slr8dfraa3g2s6bsayladhax2jccwj4kcndz"))))
       (build-system pyproject-build-system)
-      (native-inputs (list python-flexmock python-pytest python-pytest-cov
-                           python-setuptools python-wheel))
+      (native-inputs
+       (list python-flexmock
+             python-pytest
+             python-pytest-cov
+             python-setuptools
+             python-six))
       (home-page "https://github.com/oinume/iocapture")
       (synopsis "Python capturing tool for stdout and stderr")
       (description
@@ -34095,6 +34107,8 @@ to minimize duplication of information across files.  The format supports schema
 validation.")
     (license license:lgpl3)))
 
+;; XXX: Not maintained since 2021, there is no git available as seen in
+;; <https://pypi.org/project/flufl.bounce>.
 (define-public python-flufl-bounce
   (package
     (name "python-flufl-bounce")
@@ -34106,7 +34120,7 @@ validation.")
         (sha256
          (base32
           "0c9qc2l47lyqnpwskp6vvi7m3jqh6hx42v6d35dgxh3fjzmlll15"))))
-    (build-system python-build-system)
+    (build-system pyproject-build-system)
     (arguments
      (list #:phases
            #~(modify-phases %standard-phases
@@ -34119,7 +34133,7 @@ validation.")
     (propagated-inputs
      (list python-atpublic python-zope-interface))
     (native-inputs
-     (list python-flufl-testing python-nose2))
+     (list python-flufl-testing python-nose2 python-setuptools))
     (home-page "https://fluflbounce.readthedocs.io/en/latest/")
     (synopsis "Email bounce detectors")
     (description "The @code{flufl.bounce} library provides a set of heuristics
@@ -36879,6 +36893,35 @@ systems in Python.")
 key-value pairs from a @code{.env} file and set them as environment variables.")
     (license license:bsd-3)))
 
+;; Old version just for docker-compose; remove once that is updated.
+(define-public python-dotenv-0.13.0
+  (package (inherit python-dotenv)
+    (name "python-dotenv")
+    (version "0.13.0")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "python-dotenv" version))
+       (sha256
+        (base32
+         "0x5dagmfn31phrbxlwacw3s4w5vibv8fxqc62nqcdvdhjsy0k69v"))))
+    (arguments
+     `(#:phases
+       (modify-phases %standard-phases
+         (replace 'check
+           (lambda* (#:key tests? inputs outputs #:allow-other-keys)
+             (when tests?
+               (add-installed-pythonpath inputs outputs)
+               (setenv "PATH" (string-append (getenv "PATH") ":"
+                                             (assoc-ref outputs "out") "/bin"))
+               ;; Skip the ipython tests.
+               (delete-file "tests/test_ipython.py")
+               (invoke "python" "-m" "pytest")))))))
+    (native-inputs
+     (modify-inputs (package-native-inputs python-dotenv)
+       (append python-mock)
+       (replace "python-sh" python-sh-1)))))
+
 (define-public date2name
   (let ((commit "6c8f37277e8ec82aa50f90b8921422be30c4e798")
         (revision "1"))
@@ -37943,6 +37986,43 @@ static types.")
     (description "This package providis typing stubs for python-dateutil.")
     (license license:asl2.0)))
 
+(define-public python-types-aiofiles
+  (package
+    (name "python-types-aiofiles")
+    (version "24.1.0.20250822")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "types_aiofiles" version))
+       (sha256
+        (base32 "0ysar1an6il2rsd54fwzwdis209z3qq3i4zhgixfjzrh1j70vfcs"))))
+    (build-system pyproject-build-system)
+    (arguments (list #:tests? #f))      ;no tests in PyPI archive
+    (native-inputs (list python-setuptools))
+    (home-page "https://github.com/python/typeshed")
+    (synopsis "Typing stubs for python-aiofiles")
+    (description "This package providis typing stubs for python-aiofiles.")
+    (license license:asl2.0)))
+
+(define-public python-types-tqdm
+  (package
+    (name "python-types-tqdm")
+    (version "4.67.0.20250809")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "types_tqdm" version))
+       (sha256
+        (base32 "006md2hnsq79p7d5z3kiaapvl9wwa4dz3yb39jf0n22n2awpmgq2"))))
+    (build-system pyproject-build-system)
+    (arguments (list #:tests? #f))      ;no tests in PyPI archive
+    (native-inputs (list python-setuptools))
+    (propagated-inputs (list python-types-requests))
+    (home-page "https://github.com/python/typeshed")
+    (synopsis "Typing stubs for python-tqdm")
+    (description "This package providis typing stubs for python-tqdm.")
+    (license license:asl2.0)))
+
 (define-public python-types-docutils
   (package
     (name "python-types-docutils")
@@ -39348,7 +39428,19 @@ client library.")
        (sha256
         (base32 "122a8prbcj070y3fl82kvxmbciv36hj1h1d448l6zcdrb22q4mhx"))))
     (build-system pyproject-build-system)
-    (native-inputs (list python-setuptools python-wheel))
+    (arguments
+     (list
+      ;; tests: 1571 passed, 37 deselected, 1 warning
+      ;;
+      ;; Two test fail with assertion not equal:
+      ;;
+      ;; test_decode_error[0001-unpack_from requires a buffer of at least 1
+      ;; bytes] - AssertionError
+      ;;
+      ;; test_decode_error[00000101-unpack_from requires a buffer of at least
+      ;; 1 bytes] - AssertionError
+      #:test-flags #~(list "-k" "not test_decode_error")))
+    (native-inputs (list python-pytest python-setuptools))
     (home-page "https://ndeflib.readthedocs.io/")
     (synopsis "NFC Data Exchange Format decoder and encoder.")
     (description "This package provides a NFC (Near-Field Communication)
@@ -39759,6 +39851,24 @@ package.  It can be used by type-checking tools like mypy, PyCharm, pytype
 etc. to check code that uses @code{orjson}.")
     (license license:asl2.0)))
 
+(define-public python-types-regex
+  (package
+    (name "python-types-regex")
+    (version "2025.9.18.20250921")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (pypi-uri "types_regex" version))
+       (sha256
+        (base32 "0gqc8b9d38pdm1l6nryi9rq9vmpis575hqnxlvj904n3n4hhqw71"))))
+    (build-system pyproject-build-system)
+    (arguments (list #:tests? #f))      ;no tests in PyPI archive
+    (native-inputs (list python-setuptools))
+    (home-page "https://github.com/python/typeshed")
+    (synopsis "Typing stubs for regex")
+    (description "This package provides typing stubs for regex.")
+    (license license:asl2.0)))
+
 (define-public python-rpds-py
   (package
     (name "python-rpds-py")
@@ -40103,8 +40213,16 @@ read all zbar supported codes.")
                (base32
                 "0r46q4hd7xbpvnidbra1prkg4xhmajxjjmclfqgp3pv0lgyslqxh"))))
     (build-system pyproject-build-system)
+    (arguments
+     ;; XXX: No tests in PyPI, tere are tests in Git, but there is no 3.7.10.1
+     ;; tag.
+     ;;
+     ;; See:
+     ;; - URL: <https://raw.githubusercontent.com/zeroc-ice>
+     ;; - File: <ice/refs/heads/main/python/allTests.py>
+     (list #:tests? #f))
     (inputs (list openssl))
-    (native-inputs (list python-setuptools python-wheel))
+    (native-inputs (list python-setuptools))
     (home-page "https://zeroc.com")
     (synopsis "RPC framework")
     (description
@@ -40113,6 +40231,29 @@ software by taking care of all interactions with low-level network programming
 interfaces.")
     (license license:gpl2)))
 
+;; Package variant to build python-omero-py@5.20.0
+(define-public python-zeroc-ice-3.6
+  (package
+    (inherit python-zeroc-ice)
+    (version "3.6.5")
+    (source (origin
+              (method url-fetch)
+              (uri (pypi-uri "zeroc-ice" version))
+              (sha256
+               (base32
+                "0mikjfvq26kh8asnn9v55z41pap4c5ypymqnwwi4xkavc3mzyda2"))
+              (patches
+               (search-patches
+                "python-zeroc-ice-3.6.5-python-3.11-support.patch"))))
+    (arguments
+     (substitute-keyword-arguments (package-arguments python-zeroc-ice)
+       ((#:phases phases #~%standard-phases)
+        #~(modify-phases #$phases
+            (add-before 'build 'relax-gcc-14-strictness
+              (lambda _
+                (setenv "CFLAGS"
+                        "-g -O2  -Wno-error=implicit-function-declaration")))))))))
+
 (define-public python-islenska
   (package
     (name "python-islenska")
@@ -40213,20 +40354,6 @@ instance in spelling correction, predictive typing, to help disabled people
 write text fast, and for various text generation, statistics, and modeling tasks.")
     (license license:expat)))
 
-(define-public python-zeroc-ice-3.6
-  (package
-    (inherit python-zeroc-ice)
-    (version "3.6.5")
-    (source (origin
-              (method url-fetch)
-              (uri (pypi-uri "zeroc-ice" version))
-              (sha256
-               (base32
-                "0mikjfvq26kh8asnn9v55z41pap4c5ypymqnwwi4xkavc3mzyda2"))
-              (patches
-               (search-patches
-                "python-zeroc-ice-3.6.5-python-3.11-support.patch"))))))
-
 (define-public python-whenever
   (package
     (name "python-whenever")
diff --git a/gnu/packages/qt.scm b/gnu/packages/qt.scm
index 3ad2181530b..646ef54357a 100644
--- a/gnu/packages/qt.scm
+++ b/gnu/packages/qt.scm
@@ -4793,6 +4793,8 @@ PySide2, PyQt6, PySide6) and additional custom QWidgets.")
         (base32 "07rvfwzjl378j75j2va0c6xylwx16icxa6dycsjgjc329pgpng40"))))
     (build-system python-build-system)
     (native-inputs (list python-pyqt))
+    (arguments
+     (list #:tests? #f)) ; No tests
     (home-page "https://github.com/mottosso/Qt.py")
     (synopsis "Abstraction layer for Python Qt bindings")
     (description
diff --git a/gnu/packages/radio.scm b/gnu/packages/radio.scm
index e846ce973d4..104f56442d8 100644
--- a/gnu/packages/radio.scm
+++ b/gnu/packages/radio.scm
@@ -766,6 +766,8 @@ a local network link.")
            python-wheel))
     (propagated-inputs
      (list python-numpy soapysdr))
+    (arguments
+     (list #:tests? #f)) ; No tests
     (home-page "https://github.com/xmikos/simplesoapy")
     (synopsis "Python wrapper for SoapySDR")
     (description
@@ -820,7 +822,8 @@ devices that are supported by the SoapySDR library.")
            python-simplesoapy
            soapy-power))
     (arguments
-     (list #:phases
+     (list #:tests? #f ; No tests
+           #:phases
            #~(modify-phases %standard-phases
                (add-after 'install 'wrap-path
                  ;; Add the location of the default backend to PATH.
diff --git a/gnu/packages/rednotebook.scm b/gnu/packages/rednotebook.scm
index 6d61fa13911..6dcc8a2cac1 100644
--- a/gnu/packages/rednotebook.scm
+++ b/gnu/packages/rednotebook.scm
@@ -18,21 +18,25 @@
 ;;; along with GNU Guix.  If not, see <http://www.gnu.org/licenses/>.
 
 (define-module (gnu packages rednotebook)
+  #:use-module (guix gexp)
   #:use-module (guix packages)
   #:use-module (guix git-download)
-  #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (gnu packages bash)
-  #:use-module (gnu packages python)
+  #:use-module (gnu packages check)
+  #:use-module (gnu packages gettext)
   #:use-module (gnu packages glib)
   #:use-module (gnu packages gtk)
-  #:use-module (gnu packages webkit)
-  #:use-module (gnu packages python-xyz))
+  #:use-module (gnu packages python)
+  #:use-module (gnu packages python-build)
+  #:use-module (gnu packages python-xyz)
+  #:use-module (gnu packages webkit))
 
 (define-public rednotebook
   (package
     (name "rednotebook")
-    (version "2.22")
+    (version "2.41")
     (source
      (origin
        (method git-fetch)
@@ -41,35 +45,36 @@
              (commit (string-append "v" version))))
        (file-name (git-file-name name version))
        (sha256
-        (base32 "11n970ad0j57vlll5j30ngkrfyil23v1b29ickbnblcldvjbgwa5"))))
-    (build-system python-build-system)
+        (base32 "1nljj227lykl4gq1qvvv0pj00k8pbi3njm4agz7wsfcihz6dlrxi"))))
+    (build-system pyproject-build-system)
     (arguments
-     ;; Tests fail to find the "_" function.
-     ;; It should be defined in rednotebook/info.py if '_' is not a member of
-     ;; 'builtins'. It is either not defined or not exported during the check
-     ;; phase. The program does not have this problem after it is installed.
-     ;; TODO: Fix tests.
-     `(#:tests? #f
-       #:imported-modules ((guix build glib-or-gtk-build-system)
-                           ,@%python-build-system-modules)
-       #:modules ((ice-9 match)
-                  (guix build python-build-system)
-                  ((guix build glib-or-gtk-build-system) #:prefix glib-or-gtk:)
-                  (guix build utils))
-       #:phases
-       (modify-phases %standard-phases
-         ;; Make sure rednotebook can find the typelibs and webkitgtk shared
-         ;; libraries.
-         (add-before 'wrap 'wrap-with-library-paths
-           (lambda* (#:key inputs outputs #:allow-other-keys)
-             (let ((out (assoc-ref outputs "out"))
-                   (gi-typelib-path (getenv "GI_TYPELIB_PATH"))
-                   (webkitgtk-path (string-append
-                                    (assoc-ref inputs "webkitgtk-for-gtk3")
-                                    "/lib")))
-               (wrap-program (string-append out "/bin/rednotebook")
-                 `("GI_TYPELIB_PATH" ":" prefix (,gi-typelib-path))
-                 `("LD_LIBRARY_PATH" ":" prefix (,webkitgtk-path)))))))))
+     (list
+      #:imported-modules
+      `((guix build glib-or-gtk-build-system)
+        ,@%pyproject-build-system-modules)
+      #:modules
+      `((ice-9 match)
+        (guix build pyproject-build-system)
+        ((guix build glib-or-gtk-build-system) #:prefix glib-or-gtk:)
+        (guix build utils))
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'check 'configure-tests
+            (lambda _
+              (setenv "HOME" (getcwd))))
+          ;; Make sure rednotebook can find the typelibs and webkitgtk shared
+          ;; libraries.
+          (add-before 'wrap 'wrap-with-library-paths
+            (lambda* (#:key inputs outputs #:allow-other-keys)
+              (let ((webkitgtk-bin (search-input-file inputs
+                                                      "bin/WebKitWebDriver")))
+                (wrap-program (string-append #$output "/bin/rednotebook")
+                  `("GI_TYPELIB_PATH" ":" prefix
+                    (,(getenv "GI_TYPELIB_PATH")))
+                  `("LD_LIBRARY_PATH" ":" prefix
+                    (,(string-append (dirname (dirname webkitgtk-bin))
+                                     "/lib"))))))))))
+    (native-inputs (list gettext-minimal python-pytest python-setuptools))
     (inputs
      (list bash-minimal
            gtk+
@@ -79,7 +84,7 @@
            webkitgtk-for-gtk3))
     ;; TODO: package the following for python3 (if possible), add them as
     ;; dependencies, and remove them from rednotebook source:
-    ;; pygtkspellcheck, elib.intl, msgfmt, txt2tags
+    ;; pygtkspellcheck, elib.intl, txt2tags
     ;; TODO: package and add pyenchant for python3 and add it as a dependency.
     (home-page "https://www.rednotebook.app")
     (synopsis "Daily journal with calendar, templates and keyword searching")
diff --git a/gnu/packages/search.scm b/gnu/packages/search.scm
index c0e3654fd8f..6a045477e72 100644
--- a/gnu/packages/search.scm
+++ b/gnu/packages/search.scm
@@ -42,7 +42,7 @@
   #:use-module (guix utils)
   #:use-module (guix build-system gnu)
   #:use-module (guix build-system perl)
-  #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module (guix build-system meson)
   #:use-module (gnu packages)
   #:use-module (gnu packages adns)
@@ -71,6 +71,7 @@
   #:use-module (gnu packages pdf)
   #:use-module (gnu packages photo)
   #:use-module (gnu packages python)
+  #:use-module (gnu packages python-build)
   #:use-module (gnu packages python-crypto)
   #:use-module (gnu packages python-web)
   #:use-module (gnu packages python-xyz)
@@ -640,65 +641,72 @@ search the generated indexes.")
     (source
      (origin
        (method url-fetch)
-       (uri (string-append
-             "https://finestructure.net/xapers/releases/xapers-"
-             version ".tar.gz"))
+       (uri (string-append "https://finestructure.net/xapers/releases/xapers-"
+                           version ".tar.gz"))
        (sha256
-        (base32
-         "0ykz6hn3qj46w3c99d6q0pi5ncq2894simcl7vapv047zm3cylmd"))))
-    (build-system python-build-system)
-    (propagated-inputs
-     (list poppler python-urwid xclip xdg-utils))
-    (inputs
-     (list python-latexcodec
-           python-pybtex
-           python-pycurl
-           python-pyyaml
-           python-six
-           python-xapian-bindings))
+        (base32 "0ykz6hn3qj46w3c99d6q0pi5ncq2894simcl7vapv047zm3cylmd"))))
+    (build-system pyproject-build-system)
     (arguments
-     `(#:modules ((ice-9 rdelim)
-                  (guix build python-build-system)
+     (list
+      #:tests? #f                   ; A lot of tests are failing, unclear why.
+      #:modules `((ice-9 rdelim)
+                  (guix build pyproject-build-system)
                   (guix build utils))
-       #:phases
-       (modify-phases %standard-phases
-         (add-after 'install 'install-doc
-           (lambda* (#:key inputs outputs #:allow-other-keys)
-             (define (purge-term-support input output)
-               (let loop ((line (read-line input)))
-                 (if (string-prefix? "if [[ \"$term\"" line)
-                     (begin (display "eval \"$cmd\"\n" output)
-                            #t)
-                     (begin (display (string-append line "\n") output)
-                            (loop (read-line input))))))
-             (let* ((out (assoc-ref outputs "out"))
-                    (bin (string-append out "/bin"))
-                    (adder-out (string-append bin "/xapers-adder"))
-                    (man1 (string-append out "/share/man/man1")))
-               (install-file "man/man1/xapers.1"  man1)
-               (install-file "man/man1/xapers-adder.1" man1)
-               ;; below is equivalent to setting --no-term option
-               ;; permanently on; this is desirable to avoid imposing
-               ;; an x-terminal installation on the user but breaks
-               ;; some potential xapers-adder uses like auto browser
-               ;; pdf handler, but user could instead still use
-               ;; e.g. "xterm -e xapers-adder %F" for same use.
-               ;; alternatively we could propagate xterm as an input
-               ;; and replace 'x-terminal-emulator' with 'xterm'
-               (call-with-input-file "bin/xapers-adder"
-                 (lambda (input)
-                   (call-with-output-file adder-out
-                     (lambda (output)
-                       (purge-term-support input output)))))
-               (chmod adder-out #o555)))))))
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-after 'install 'install-doc
+            (lambda* (#:key inputs outputs #:allow-other-keys)
+              (define (purge-term-support input output)
+                (let loop
+                    ((line (read-line input)))
+                  (if (string-prefix? "if [[ \"$term\"" line)
+                      (display "eval \"$cmd\"\n" output)
+                      (begin
+                        (display (string-append line "\n") output)
+                        (loop (read-line input))))))
+              (let* ((bin (string-append #$output "/bin"))
+                     (adder-out (string-append bin "/xapers-adder"))
+                     (man1 (string-append #$output "/share/man/man1")))
+                (install-file "man/man1/xapers.1" man1)
+                (install-file "man/man1/xapers-adder.1" man1)
+                ;; below is equivalent to setting --no-term option
+                ;; permanently on; this is desirable to avoid imposing
+                ;; an x-terminal installation on the user but breaks
+                ;; some potential xapers-adder uses like auto browser
+                ;; pdf handler, but user could instead still use
+                ;; e.g. "xterm -e xapers-adder %F" for same use.
+                ;; alternatively we could propagate xterm as an input
+                ;; and replace 'x-terminal-emulator' with 'xterm'
+                (mkdir-p (dirname adder-out))
+                (call-with-input-file "bin/xapers-adder"
+                  (lambda (input)
+                    (call-with-output-file adder-out
+                      (lambda (output)
+                        (purge-term-support input output)))))
+                (chmod adder-out #o555))))
+          (replace 'check
+            (lambda* (#:key tests? #:allow-other-keys)
+              (if tests?
+                  (with-directory-excursion "test"
+                    (setenv "HOME" (getcwd))
+                    (invoke "bash" "all"))
+                  (format #t "test suite not run~%")))))))
+    (native-inputs (list python-setuptools))
+    (propagated-inputs (list poppler python-urwid xclip xdg-utils))
+    (inputs (list python-latexcodec
+                  python-pybtex
+                  python-pycurl
+                  python-pyyaml
+                  python-six
+                  python-xapian-bindings))
     (home-page "https://finestructure.net/xapers/")
     (synopsis "Personal document indexing system")
     (description
-     "Xapers is a personal document indexing system,
-geared towards academic journal articles build on the Xapian search engine.
-Think of it as your own personal document search engine, or a local cache of
-online libraries.  It provides fast search of document text and
-bibliographic data and simple document and bibtex retrieval.")
+     "Xapers is a personal document indexing system, geared towards academic
+journal articles build on the Xapian search engine. Think of it as your own
+personal document search engine, or a local cache of online libraries.  It
+provides fast search of document text and bibliographic data and simple
+document and bibtex retrieval.")
     (license license:gpl3+)))
 
 (define-public ugrep
diff --git a/gnu/packages/shellutils.scm b/gnu/packages/shellutils.scm
index bc52898c0ae..71d9cee818c 100644
--- a/gnu/packages/shellutils.scm
+++ b/gnu/packages/shellutils.scm
@@ -69,6 +69,7 @@
   #:use-module (gnu packages pkg-config)
   #:use-module (gnu packages python)
   #:use-module (gnu packages python-build)
+  #:use-module (gnu packages python-check)
   #:use-module (gnu packages python-xyz)
   #:use-module (gnu packages readline)
   #:use-module (gnu packages ruby)
diff --git a/gnu/packages/stenography.scm b/gnu/packages/stenography.scm
index 687a23e85a4..3f0979c3063 100644
--- a/gnu/packages/stenography.scm
+++ b/gnu/packages/stenography.scm
@@ -45,17 +45,21 @@
   (package
     (name "python-plover-stroke")
     (version "1.1.0")
-    (source (origin
-              (method url-fetch)
-              (uri (pypi-uri "plover_stroke" version))
-              (sha256
-               (base32
-                "0lyifam9xqpx2jzqcbah84sv909n4g2frm7pd5gvcrpf98zv40yy"))))
-    (build-system python-build-system)
-    (native-inputs (list python-pytest))
+    (source
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/benoit-pierre/plover_stroke")
+             (commit version)))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "104ab1lr2xr8nbq98n7h3jvskfzzg8m41rhb1ik4b7w474rlxgh3"))))
+    (build-system pyproject-build-system)
+    (native-inputs (list python-pytest python-setuptools))
     (home-page "https://github.com/benoit-pierre/plover_stroke")
     (synopsis "Stroke handling helper library for Plover")
-    (description "This package provides a helper class for working with steno strokes.")
+    (description
+     "This package provides a helper class for working with steno strokes.")
     (license license:gpl2+)))
 
 (define-public plover
diff --git a/gnu/packages/task-management.scm b/gnu/packages/task-management.scm
index 0a978f9c9f3..f61f7ec99e8 100644
--- a/gnu/packages/task-management.scm
+++ b/gnu/packages/task-management.scm
@@ -92,20 +92,16 @@
          (file-name (git-file-name name version))
          (sha256
           (base32 "1nyx80z53xxlbhpb5k22jnv4jajxqhjm0gz7qb18w9pqqlrvkqd4"))))
-      (build-system python-build-system)
+      (build-system pyproject-build-system)
       (arguments
        (list
         #:phases
         #~(modify-phases %standard-phases
-            (replace 'check
-              (lambda* (#:key inputs outputs tests? #:allow-other-keys)
-                (setenv "HOME" (getenv "TEMP"))
-                (when tests?
-                  (add-installed-pythonpath inputs outputs)
-                  (invoke "pytest" "-vv")))))))
+            (add-before 'check 'configure-tests
+              (lambda _
+                (setenv "HOME" (getenv "TEMP")))))))
       (native-inputs
-       (list python-pytest
-             python-click))
+       (list python-pytest python-click python-setuptools))
       (inputs
        (list python-click
              python-click-default-group
diff --git a/gnu/packages/tree-sitter.scm b/gnu/packages/tree-sitter.scm
index 762bd6ef42d..7d48a5a4afc 100644
--- a/gnu/packages/tree-sitter.scm
+++ b/gnu/packages/tree-sitter.scm
@@ -9,6 +9,7 @@
 ;;; Copyright © 2023, 2024 Raven Hallsby <karl@hallsby.com>
 ;;; Copyright © 2024 Foundation Devices, Inc. <hello@foundation.xyz>
 ;;; Copyright © 2025 Andrew Wong <wongandj@icloud.com>
+;;; Copyright © 2025 Nguyễn Gia Phong <mcsinyx@disroot.org>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -530,6 +531,14 @@ which will be used as a snippet in origin."
      #:commit commit
      #:license license:asl2.0)))
 
+(define-public tree-sitter-janet
+  (tree-sitter-grammar
+   "janet" "Janet"
+   "1sg862gqxn5y86sqa4habyicsr1ax70i7w8ibnn2yyx1bzn99jqn"
+   "0.1.0"
+   #:repository-url "https://github.com/GrayJack/tree-sitter-janet"
+   #:license license:bsd-3))
+
 (define-public tree-sitter-java
   (tree-sitter-grammar
    "java" "Java"
diff --git a/gnu/packages/tryton.scm b/gnu/packages/tryton.scm
index ee6cc9b6bfc..0261e92e8e7 100644
--- a/gnu/packages/tryton.scm
+++ b/gnu/packages/tryton.scm
@@ -33,6 +33,7 @@
   #:use-module (gnu packages gnome)
   #:use-module (gnu packages graphviz)
   #:use-module (gnu packages gtk)
+  #:use-module (gnu packages iso-codes)
   #:use-module (gnu packages pdf)
   #:use-module (gnu packages python)
   #:use-module (gnu packages python-build)
@@ -1739,7 +1740,7 @@ month and a year of work.")
     (arguments (tryton-arguments "country" "--no-doctest"))
     (native-inputs (%standard-trytond-native-inputs))
     (propagated-inputs
-     (list python-pycountry@20.7.3 trytond))
+     (list python-pycountry-20.7.3 trytond))
     (home-page "http://www.tryton.org/")
     (synopsis "Tryton module with countries")
     (description
diff --git a/gnu/packages/video.scm b/gnu/packages/video.scm
index 0db72149759..f0f23e6f8d8 100644
--- a/gnu/packages/video.scm
+++ b/gnu/packages/video.scm
@@ -74,6 +74,7 @@
 ;;; Copyright © 2025 Sharlatan Hellseher <sharlatanus@gmail.ccom>
 ;;; Copyright © 2025 VnPower <vnpower@loang.net>
 ;;; Copyright © 2025 Zhu Zihao <all_but_last@163.com>
+;;; Copyright © 2025 Remco van 't Veer <remco@remworks.net>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -3138,7 +3139,7 @@ video streaming services of the Finnish national broadcasting company Yle.")
 (define-public yt-dlp
   (package
     (name "yt-dlp")
-    (version "2025.09.23")
+    (version "2025.09.26")
     (source
      (origin
        (method git-fetch)
@@ -3150,7 +3151,7 @@ video streaming services of the Finnish national broadcasting company Yle.")
        (snippet #~(substitute* "pyproject.toml"
                     (("^.*Programming Language :: Python :: 3\\.13.*$") "")))
        (sha256
-        (base32 "0x6yjvv0wwyx10bpk2s06k8amah4q6v1g2plwrng1ap2jza539x6"))))
+        (base32 "0j6l2zskmsvqk8h3ialbymk75i0bfzn2qmc2gk6s1ybhnpryrv7y"))))
     (build-system pyproject-build-system)
     (arguments
      (list
@@ -3172,7 +3173,7 @@ video streaming services of the Finnish national broadcasting company Yle.")
                   "'\n")))))
           (add-before 'build 'build-generated-files
             (lambda* (#:key inputs #:allow-other-keys)
-              (if (search-input-file inputs "bin/pandoc")
+              (if (which "pandoc")
                   (invoke "make"
                           "PYTHON=python"
                           "yt-dlp"
diff --git a/gnu/packages/weather.scm b/gnu/packages/weather.scm
index 18f392ccf54..6a89c651036 100644
--- a/gnu/packages/weather.scm
+++ b/gnu/packages/weather.scm
@@ -20,13 +20,14 @@
 (define-module (gnu packages weather)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (guix build-system go)
-  #:use-module (guix build-system python)
+  #:use-module (guix build-system pyproject)
   #:use-module (guix gexp)
   #:use-module (guix git-download)
   #:use-module (guix packages)
   #:use-module (gnu packages)
   #:use-module (gnu packages golang-build)
   #:use-module (gnu packages golang-xyz)
+  #:use-module (gnu packages python-build)
   #:use-module (gnu packages qt)
   #:use-module (gnu packages xml))
 
@@ -65,30 +66,35 @@ precipitation amount and probability.")
     (name "meteo-qt")
     (version "4.2")
     (source
-     (origin (method git-fetch)
-             (uri (git-reference (url "https://github.com/dglent/meteo-qt")
-                                 (commit (string-append "v" version))))
-             (file-name (git-file-name name version))
-             (sha256
-              (base32 "1cvmh5rq50dncd2fmp4amjb2hhl2mryb2ywg0zdzhz89dkjq0kdk"))))
-    (build-system python-build-system)
-    (native-inputs (list python-pyqt-6))
-    (propagated-inputs (list python-lxml python-pyqt-6 python-sip))
+     (origin
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://github.com/dglent/meteo-qt")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "1cvmh5rq50dncd2fmp4amjb2hhl2mryb2ywg0zdzhz89dkjq0kdk"))))
+    (build-system pyproject-build-system)
     (arguments
-     (list #:phases
-           #~(modify-phases %standard-phases
-               (add-before 'build 'remove-translations
-                 (lambda _
-                   ;; Translation processing is broken because Guix thinks lprodump
-                   ;; is in qtbase, not qttools. So, we'll skip it and exclude
-                   ;; qttools from the native input list until it is fixed.
-                   (substitute* "setup.py"
-                     (("/usr") #$output)
-                     (("^.+lrelease-pro-qt6.+$") "")
-                     (("^.+meteo_qt/translations.+$") "")))))))
+     (list
+      #:tests? #f                       ; No tests.
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'build 'remove-translations
+            (lambda _
+              ;; Translation processing is broken because Guix thinks lprodump
+              ;; is in qtbase, not qttools. So, we'll skip it and exclude
+              ;; qttools from the native input list until it is fixed.
+              (substitute* "setup.py"
+                (("/usr") #$output)
+                (("^.+lrelease-pro-qt6.+$") "")
+                (("^.+meteo_qt/translations.+$") "")))))))
+    (native-inputs (list python-pyqt-6 python-setuptools))
+    (propagated-inputs (list python-lxml python-pyqt-6 python-sip))
     (home-page "https://github.com/dglent/meteo-qt")
     (synopsis "Weather application for the system tray")
-    (description "meteo-qt is an application to display weather information in
-desktop panels, desktop notifictions and its own window.  Weather information is
+    (description
+     "meteo-qt is an application to display weather information in desktop
+panels, desktop notifictions and its own window.  Weather information is
 retrieved from OpenWeatherMap.")
     (license license:gpl3)))
diff --git a/gnu/packages/web-browsers.scm b/gnu/packages/web-browsers.scm
index 5940ca54188..aa55af927a5 100644
--- a/gnu/packages/web-browsers.scm
+++ b/gnu/packages/web-browsers.scm
@@ -48,7 +48,6 @@
   #:use-module (guix build-system go)
   #:use-module (guix build-system meson)
   #:use-module (guix build-system pyproject)
-  #:use-module (guix build-system python)
   #:use-module (guix download)
   #:use-module (guix gexp)
   #:use-module (guix git-download)
@@ -1095,7 +1094,9 @@ with a terminal interface, for Gemini also a GUI is available.")
          (file-name (git-file-name name version))
          (sha256
           (base32 "0jp4v4jw82qqynqqs7x35g5yvm1sd48cvbqh7j2r1ixw1z6ldhc4"))))
-      (build-system python-build-system)
+      (build-system pyproject-build-system)
+      (arguments (list #:tests? #f))    ; No tests.
+      (native-inputs (list python-setuptools))
       (home-page "https://github.com/xyzshantaram/leo")
       (synopsis "Gemini client written in Python")
       (description
@@ -1107,21 +1108,31 @@ saved to a file for further viewing in another window.")
 (define-public av-98
   (package
     (name "av-98")
-    (version "1.0.1")
-    (properties
-     '((upstream-name . "AV-98")))
+    (version "1.4")
+    (properties '((upstream-name . "AV-98")))
     (source
      (origin
-       (method url-fetch)
-       (uri (pypi-uri "AV-98" version))
+       (method git-fetch)
+       (uri (git-reference
+             (url "https://git.sr.ht/~solderpunk/AV-98")
+             (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
        (sha256
-        (base32
-         "02fjnc2rvm010gb3i07p8r4xlhrmnv1wca1qymfjcymr7vm68h0i"))))
-    (build-system python-build-system)
-    (home-page "https://tildegit.org/solderpunk/AV-98/")
+        (base32 "04dzkzsan1cnrslsvfgn1whpwald8xy34wqzvq81hd2mvw9a2n69"))))
+    (build-system pyproject-build-system)
+    (arguments
+     (list
+      #:tests? #f                       ; No tests.
+      #:phases
+      #~(modify-phases %standard-phases
+          (add-before 'sanity-check 'configure-sanity-check
+            (lambda _
+              (setenv "HOME" (getcwd)))))))
+    (native-inputs (list python-setuptools))
+    (home-page "https://git.sr.ht/~solderpunk/AV-98")
     (synopsis "Command line Gemini client")
-    (description "AV-98 is an experimental client for the Gemini protocol.
-Features include
+    (description
+     "AV-98 is an experimental client for the Gemini protocol. Features include
 @itemize
 @item TOFU or CA server certificate validation;
 @item Extensive client certificate support if an openssl binary is available;
diff --git a/gnu/packages/wm.scm b/gnu/packages/wm.scm
index 7b91e2b33a0..e4853c589b6 100644
--- a/gnu/packages/wm.scm
+++ b/gnu/packages/wm.scm
@@ -1,11 +1,12 @@
 ;;; GNU Guix --- Functional package management for GNU
+;;; Copyright © 2014 Julien Lepiller <julien@lepiller.eu>
 ;;; Copyright © 2015 Eric Dvorsak <eric@dvorsak.fr>
 ;;; Copyright © 2015 Siniša Biđin <sinisa@bidin.eu>
 ;;; Copyright © 2015, 2016, 2022 Eric Bavier <bavier@posteo.net>
 ;;; Copyright © 2015 xd1le <elisp.vim@gmail.com>
 ;;; Copyright © 2015 Paul van der Walt <paul@denknerd.org>
 ;;; Copyright © 2016 Danny Milosavljevic <dannym@scratchpost.org>
-;;; Copyright © 2016, 2019, 2020, 2023, 2024 Efraim Flashner <efraim@flashner.co.il>
+;;; Copyright © 2016, 2019-2020, 2023-2024 Efraim Flashner <efraim@flashner.co.il>
 ;;; Copyright © 2016 Al McElrath <hello@yrns.org>
 ;;; Copyright © 2016 Carlo Zancanaro <carlo@zancanaro.id.au>
 ;;; Copyright © 2016 2019, 2021-2022 Ludovic Courtès <ludo@gnu.org>
@@ -81,6 +82,7 @@
 ;;; Copyright © 2025 Tomáš Čech <sleep_walker@gnu.org>
 ;;; Copyright © 2025 Ricardo Wurmus <rekado@elephly.net>
 ;;; Copyright © 2025 Andrew Wong <wongandj@icloud.com>
+;;; Copyright © 2025 Hugo Buddelmeijer <hugo@buddelmeijer.nl>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -707,6 +709,85 @@ the i3 window manager through its i3bar component, as an alternative to
 i3status.")
     (license license:gpl3+)))
 
+(define-public obconf
+  (package
+    (name "obconf")
+    (version "2.0.4")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (string-append "http://openbox.org/dist/" name
+                           "/" name "-" version ".tar.gz"))
+       (sha256
+        (base32
+         "1fanjdmd8727kk74x5404vi8v7s4kpq48l583d12fsi4xvsfb8vi"))))
+    (inputs (list gtk+-2
+                  imlib2
+                  libglade
+                  libsm
+                  librsvg
+                  libxft
+                  openbox
+                  startup-notification))
+    (native-inputs (list gettext-minimal pkg-config))
+    (build-system gnu-build-system)
+    (arguments
+     (list
+       #:configure-flags
+         #~(list "--enable-nls"
+                 "CFLAGS=-g -O2 -Wno-error=implicit-function-declaration")))
+    (home-page "https://openbox.org/obconf")
+    (synopsis "Openbox configuration tool")
+    (description
+     "Obconf is a tool for configuring the Openbox window manager.
+You can configure its appearance, themes, and much more.")
+    (license license:gpl2+)))
+
+(define-public openbox
+  (package
+    (name "openbox")
+    (version "3.6.1")
+    (source
+     (origin
+       (method url-fetch)
+       (uri (string-append
+             "http://openbox.org/dist/openbox/" name "-"
+             version ".tar.xz"))
+       (sha256
+        (base32
+         "0vg2y1qddsdxkjv806mzpvmkgzliab8ll4s7zm7ma5jnriamirxb"))
+       (patches (search-patches "openbox-add-fix-for-glib2-exposed-segfault.patch" "openbox-python3.patch"))))
+    (build-system gnu-build-system)
+    (arguments
+     (list #:phases
+           #~(modify-phases %standard-phases
+               (add-after 'unpack 'force-reconfigure
+                 ;; This is made necessary by the openbox-python3 patch.
+                 (lambda _
+                   (delete-file "configure"))))))
+    (native-inputs (list autoconf automake gettext-minimal libtool pkg-config))
+    (propagated-inputs (list python-pyxdg))
+    (inputs (list imlib2
+                  libxml2
+                  (librsvg-for-system)
+                  libsm
+                  libxcursor
+                  libxinerama
+                  libxml2
+                  libxrandr
+                  libxft
+                  pango
+                  python-wrapper))
+    (synopsis "Box style window manager")
+    (description
+     "Openbox is a highly configurable, next generation window manager with
+extensive standards support.  The *box visual style is well known for its
+minimalistic appearance.  Openbox uses the *box visual style, while providing
+a greater number of options for theme developers than previous *box
+implementations.")
+    (home-page "http://openbox.org/wiki/Main_Page")
+    (license license:gpl2+)))
+
 (define-public papersway
   (package
     (name "papersway")
@@ -991,6 +1072,65 @@ and locate windows on all your workspaces, using an interactive dmenu
 prompt.")
       (license license:wtfpl2))))
 
+(define-public quicktile
+  ;; Latest release, 0.4.0, is 5 years old and does not use pyproject.toml yet.
+  (let ((commit "2c499beedf31d5906e86c482f70129d94e429350")
+        (revision "0"))
+    (package
+      (name "quicktile")
+      (version (git-version "0.4.0" revision commit))
+      (source
+       (origin
+         (method git-fetch)
+         (uri (git-reference
+                (url "https://github.com/ssokolow/quicktile")
+                (commit commit)))
+         (file-name (git-file-name name version))
+         (sha256
+          (base32 "08kwilln32kx2cdg1sg7ffb214fkhacchx8jd64pyjbshmradgxr"))))
+      (build-system pyproject-build-system)
+      (arguments
+       (list
+        #:test-flags
+        #~(list "tests")
+        #:phases
+        #~(modify-phases %standard-phases
+            (add-before 'check 'pre-check
+              ;; tests/test_functional.py moves windows around and thus needs
+              ;; access to an X server.
+              (lambda* (#:key tests? #:allow-other-keys)
+                (when tests?
+                  (setenv "HOME" "/tmp")
+                  (mkdir-p "/tmp/.config")
+                  (system "Xvfb :1 &")
+                  (setenv "DISPLAY" ":1")
+                  ;; First run creates /tmp/.config/quicktile.cfg.
+                  (invoke "./quicktile.sh")))))))
+      (native-inputs
+       (list openbox ;necessary for test_functional.py
+             python-pluggy
+             python-pytest
+             python-pytest-cov
+             python-setuptools
+             xorg-server-for-tests))
+      (inputs
+       (list gtk+
+             libwnck
+             python-xlib
+             python-pygobject
+             python-dbus-python))
+      ;; The actual home page https://ssokolow.com/quicktile/
+      ;; gives an SSL error.
+      (home-page "https://github.com/ssokolow/quicktile")
+      (synopsis "window-tiling hotkeys to any X11 desktop")
+      (description
+       "QuickTile is a simple utility, inspired by
+@url{https://github.com/dozius/winsplit-revolution, WinSplit Revolution} for
+Windows, which adds window-tiling keybindings to existing X11 window manager.
+It may be used as a standalone alternative to the keyboard related features of
+the Compiz Grid plugin.")
+      (license license:gpl2+))))
+
 (define-public i3lock-color
   (package
     (name "i3lock-color")
diff --git a/gnu/services/web.scm b/gnu/services/web.scm
index 3989607646e..ae33a25394d 100644
--- a/gnu/services/web.scm
+++ b/gnu/services/web.scm
@@ -19,6 +19,7 @@
 ;;; Copyright © 2023 Miguel Ángel Moreno <mail@migalmoreno.com>
 ;;; Copyright © 2024 Leo Nikkilä <hello@lnikki.la>
 ;;; Copyright © 2025 Maxim Cournoyer <maxim.cournoyer@gmail.com>
+;;; Copyright © 2025 Rodion Goritskov <rodion@goritskov.com>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -40,8 +41,10 @@
   #:use-module (gnu services shepherd)
   #:use-module (gnu services admin)
   #:use-module (gnu services configuration)
+  #:use-module (gnu services databases)
   #:use-module (gnu services getmail)
   #:use-module (gnu services mail)
+  #:use-module (gnu system file-systems)
   #:use-module (gnu system pam)
   #:use-module (gnu system shadow)
   #:use-module (gnu packages admin)
@@ -59,7 +62,9 @@
   #:use-module (gnu packages mail)
   #:use-module (gnu packages rust-apps)
   #:autoload   (guix i18n) (G_)
+  #:autoload   (gnu build linux-container) (%namespaces)
   #:use-module (guix diagnostics)
+  #:use-module (guix least-authority)
   #:use-module (guix packages)
   #:use-module (guix records)
   #:use-module (guix modules)
@@ -74,6 +79,7 @@
   #:use-module (srfi srfi-34)
   #:use-module (ice-9 match)
   #:use-module (ice-9 format)
+  #:use-module (ice-9 regex)
   #:export (httpd-configuration
             httpd-configuration?
             httpd-configuration-package
@@ -328,7 +334,23 @@
             agate-configuration-group
             agate-configuration-log-file
 
-            agate-service-type))
+            agate-service-type
+
+            miniflux-configuration
+            miniflux-configuration?
+            miniflux-configuration-listen-address
+            miniflux-configuration-base-url
+            miniflux-configuration-create-administrator-account?
+            miniflux-configuration-administrator-account-name
+            miniflux-configuration-administrator-account-password
+            miniflux-configuration-run-migrations?
+            miniflux-configuration-database-url
+            miniflux-configuration-user
+            miniflux-configuration-group
+            miniflux-configuration-log-file
+            miniflux-configuration-extra-settings
+
+            miniflux-service-type))
 
 ;;; Commentary:
 ;;;
@@ -2279,3 +2301,173 @@ root=/srv/gemini
    (default-value (agate-configuration))
    (description "Run Agate, a simple Gemini protocol server written in
 Rust.")))
+
+(define (serialize-string field-name val)
+  (format #f "~a=~a\n" field-name val))
+
+(define (string-or-file-path? val)
+  (string? val))
+(define (serialize-string-or-file-path field-name val)
+  (serialize-string (if (absolute-file-name? val)
+                        (format #f "~a_FILE" field-name) field-name) val))
+(define-maybe string-or-file-path)
+
+(define (serialize-list field-name val)
+  (string-append (string-join val "\n") "\n"))
+(define-maybe list)
+
+(define (serialize-boolean field-name val)
+  (if val (serialize-string field-name "1") (serialize-string field-name "0")))
+
+(define-configuration/no-serialization miniflux-configuration
+  (listen-address
+   (string "127.0.0.1:8080")
+   "Address to listen on.
+Use absolute path like @code{\"/var/run/miniflux/miniflux.sock\"} for a Unix socket.")
+  (base-url
+   (string "http://127.0.0.1/")
+   "Base URL to generate HTML links and base path for cookies.")
+  (create-administrator-account?
+   (boolean #f)
+   "Create an initial administrator account.")
+  (administrator-account-name
+   maybe-string-or-file-path
+   "Initial administrator account name as a string or an absolute path to a file with a account name inside.")
+  (administrator-account-password
+   maybe-string-or-file-path
+   "Initial administrator account password as a string or an absolute path to a file with a password inside.")
+  (run-migrations?
+   (boolean #t)
+   "Run database migrations during application startup.")
+  (database-url
+   (string "host=/var/run/postgresql")
+   "PostgreSQL connection string.")
+  (user
+   (string "miniflux")
+   "User name for Postgresql and system account.")
+  (group
+   (string "miniflux")
+   "Group for the system account.")
+  (log-file
+   (string "/var/log/miniflux.log")
+   "Path to the log file.")
+  (extra-settings
+   maybe-list
+   "Extra configuration parameters as a list of strings."))
+
+(define (miniflux-serialize-configuration config)
+  (match-record config <miniflux-configuration>
+                (listen-address base-url create-administrator-account?
+                                administrator-account-name administrator-account-password
+                                run-migrations? database-url extra-settings)
+    (string-append (serialize-string "LISTEN_ADDR" listen-address)
+                   (serialize-string "BASE_URL" base-url)
+                   (serialize-boolean "CREATE_ADMIN" create-administrator-account?)
+                   (serialize-maybe-string-or-file-path "ADMIN_USERNAME" administrator-account-name)
+                   (serialize-maybe-string-or-file-path "ADMIN_PASSWORD" administrator-account-password)
+                   (serialize-boolean "RUN_MIGRATIONS" run-migrations?)
+                   (serialize-string "DATABASE_URL" database-url)
+                   (serialize-maybe-list #f extra-settings))))
+
+(define (miniflux-configuration-file config)
+  (mixed-text-file "miniflux.conf" (miniflux-serialize-configuration config)))
+
+(define (pair->file-system-mapping pair previous)
+  (if (pair? pair)
+      (let ((path (car pair))
+            (writable (cdr pair)))
+        (if (or (and (string? path)
+                     (absolute-file-name? path))
+                (computed-file? path))
+            (append previous (list (file-system-mapping
+                                     (source path)
+                                     (target source)
+                                     (writable? writable))))
+            previous))
+      previous))
+
+(define (miniflux-shepherd-service config)
+  (match-record config <miniflux-configuration>
+                (user group log-file database-url listen-address
+                      administrator-account-name administrator-account-password)
+    (let ((config-file (miniflux-configuration-file config)))
+      (list (shepherd-service
+	      (documentation "Run Miniflux server")
+	      (provision '(miniflux))
+	      (requirement '(postgres networking))
+	      (start #~(make-forkexec-constructor
+		        (list #$(least-authority-wrapper
+                                 (file-append miniflux "/bin/miniflux")
+                                 #:name "miniflux"
+                                 #:user user
+                                 #:group group
+                                 #:preserved-environment-variables
+                                 (append %default-preserved-environment-variables
+                                         '("SSL_CERT_FILE"))
+                                 #:mappings
+                                 (fold pair->file-system-mapping
+                                       '()
+                                       `((,log-file . #t)
+                                         (,config-file . #f)
+                                         ("/etc/ssl/certs/ca-certificates.crt" . #f)
+                                         (,administrator-account-name . #f)
+                                         (,administrator-account-password . #f)
+                                         (,(dirname listen-address)  . #t)
+                                         ,(let* ((db-socket-match (string-match ".*host=(/[^ ]*).*" database-url))
+                                                 (db-socket (if db-socket-match (match:substring db-socket-match 1) #f)))
+                                            (if db-socket
+                                                `(,db-socket . #t)))))
+                                 #:namespaces
+                                 (fold delq %namespaces '(net user)))
+                              "-config-file"
+                              #$config-file)
+		        #:log-file #$log-file))
+              (stop #~(make-kill-destructor)))))))
+
+(define (miniflux-accounts config)
+  (match-record config <miniflux-configuration>
+                (user group)
+    `(,(user-group
+         (name group)
+         (system? #t))
+      ,(user-account
+         (name user)
+         (group group)
+         (system? #t)
+         (comment "miniflux server user")
+         (home-directory "/var/empty")
+         (shell (file-append shadow "/sbin/nologin"))))))
+
+(define (miniflux-postgresql-role config)
+  (list (postgresql-role
+          (name (miniflux-configuration-user config))
+          (create-database? #t))))
+
+(define (miniflux-log-files config)
+  (list (miniflux-configuration-log-file config)))
+
+(define (miniflux-activation-service-type config)
+  (match-record config <miniflux-configuration>
+                (user listen-address)
+    #~(begin
+        (use-modules (gnu build activation))
+        (let ((user (getpwnam #$user)))
+          (if (absolute-file-name? #$listen-address)
+              (mkdir-p/perms (dirname #$listen-address) user #o755))))))
+
+(define miniflux-service-type
+  (service-type
+    (name 'miniflux)
+    (default-value (miniflux-configuration))
+    (extensions
+     (list (service-extension account-service-type
+			      miniflux-accounts)
+	   (service-extension postgresql-role-service-type
+			      miniflux-postgresql-role)
+	   (service-extension shepherd-root-service-type
+			      miniflux-shepherd-service)
+           (service-extension log-rotation-service-type
+                              miniflux-log-files)
+           (service-extension activation-service-type
+                              miniflux-activation-service-type)))
+    (description "Run Miniflux, minimalist feed reader")))
diff --git a/gnu/tests/install.scm b/gnu/tests/install.scm
index be3de699a40..b26dc890a44 100644
--- a/gnu/tests/install.scm
+++ b/gnu/tests/install.scm
@@ -43,7 +43,6 @@
   #:use-module (gnu packages firmware)
   #:use-module (gnu packages linux)
   #:use-module (gnu packages ocr)
-  #:use-module (gnu packages openbox)
   #:use-module (gnu packages package-management)
   #:use-module (gnu packages ratpoison)
   #:use-module (gnu packages suckless)
diff --git a/gnu/tests/web.scm b/gnu/tests/web.scm
index 431996ede48..419b5f0b5bf 100644
--- a/gnu/tests/web.scm
+++ b/gnu/tests/web.scm
@@ -5,6 +5,7 @@
 ;;; Copyright © 2018 Pierre-Antoine Rouby <pierre-antoine.rouby@inria.fr>
 ;;; Copyright © 2018 Marius Bakke <mbakke@fastmail.com>
 ;;; Copyright © 2024 Maxim Cournoyer <maxim@guixotic.coop>
+;;; Copyright © 2025 Rodion Goritskov <rodion@goritskov.com>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -37,6 +38,7 @@
   #:use-module (gnu packages base)
   #:use-module (gnu packages databases)
   #:use-module (gnu packages guile-xyz)
+  #:use-module (gnu packages gnupg)
   #:use-module (gnu packages patchutils)
   #:use-module (gnu packages python)
   #:use-module (gnu packages tls)
@@ -56,7 +58,10 @@
             %test-hpcguix-web
             %test-anonip
             %test-patchwork
-            %test-agate))
+            %test-agate
+            %test-miniflux-admin-string
+            %test-miniflux-admin-file
+            %test-miniflux-socket))
 
 (define %index.html-contents
   ;; Contents of the /index.html file.
@@ -848,3 +853,190 @@ HTTP-PORT."
    (name "agate")
    (description "Connect to a running Agate service.")
    (value (run-agate-test name %agate-os %index.gmi-contents))))
+
+
+;;;
+;;; Miniflux
+;;;
+
+(define %miniflux-create-admin-credentials
+  #~(begin
+      (mkdir "/var/miniflux")
+      (call-with-output-file "/var/miniflux/admin-username"
+        (lambda (port)
+          (display "test" port)))
+      (call-with-output-file "/var/miniflux/admin-password"
+        (lambda (port)
+          (display "testpassword" port)))))
+
+(define miniflux-base-system
+  (lambda (miniflux-config)
+    (simple-operating-system
+     (simple-service 'create-admin-credentials
+                     activation-service-type
+                     %miniflux-create-admin-credentials)
+     (service dhcpcd-service-type)
+     (service postgresql-service-type
+	      (postgresql-configuration
+	        (postgresql postgresql-13)))
+     (service miniflux-service-type
+              miniflux-config))))
+
+(define %miniflux-with-admin-as-string
+  (miniflux-base-system
+   (miniflux-configuration
+    (listen-address "0.0.0.0:8080")
+    (create-administrator-account? #t)
+    (administrator-account-name "test")
+    (administrator-account-password "testpassword"))))
+
+(define %miniflux-with-admin-as-file
+  (miniflux-base-system
+   (miniflux-configuration
+    (listen-address "0.0.0.0:8080")
+    (create-administrator-account? #t)
+    (administrator-account-name "/var/miniflux/admin-username")
+    (administrator-account-password "/var/miniflux/admin-password"))))
+
+(define %miniflux-with-socket
+  (miniflux-base-system
+   (miniflux-configuration
+    (listen-address "/var/run/miniflux/miniflux.sock"))))
+
+(define* (run-miniflux-test name test-os)
+  (define os
+    (marionette-operating-system
+     test-os
+     #:imported-modules '((gnu services herd)
+                          (guix combinators))))
+
+  (define forwarded-port 8080)
+
+  (define vm
+    (virtual-machine
+      (operating-system os)
+      (memory-size 512)
+      (port-forwardings `((8080 . ,forwarded-port)))))
+
+  (define test
+    (with-extensions (list guile-gcrypt)
+      (with-imported-modules '((gnu build marionette))
+        #~(begin
+            (use-modules (srfi srfi-64)
+		         (srfi srfi-11)
+                         (gnu build marionette)
+		         (web client)
+		         (web uri)
+                         (web response)
+		         (ice-9 match)
+                         (ice-9 iconv)
+                         (gcrypt base64))
+
+            (define marionette
+              (make-marionette (list #$vm)))
+
+            (test-runner-current (system-test-runner #$output))
+            (test-begin #$name)
+
+	    (test-assert "Check Miniflux service is running"
+	      (begin
+	        (#$retry-on-error
+	         (lambda ()
+		   (marionette-eval
+		    '(begin
+		       (use-modules (gnu services herd))
+		       (match (start-service '#$(string->symbol "miniflux"))
+		         (#f #f)
+		         (('service response-parts ...)
+			  (match (assq-ref response-parts 'running)
+			    (#f #f)
+			    ((running) #t)))))
+		    marionette))
+	         #:delay 1
+	         #:times 10)))
+
+            (test-assert "Miniflux TCP port ready, IPv4"
+              (wait-for-tcp-port #$forwarded-port marionette))
+
+	    (test-assert "Miniflux login page is opened"
+              (begin
+                (wait-for-tcp-port #$forwarded-port marionette)
+                (#$retry-on-error
+                 (lambda ()
+                   (let-values (((_ text)
+                                 (http-get
+				  #$(format #f "http://localhost:~A/" forwarded-port)
+				  #:decode-body? #t)))
+                     (string-contains text "<title>Sign In - Miniflux</title>")))
+                 #:times 10
+                 #:delay 2)))
+
+            (define authorization-header
+              (let ((encoded (base64-encode (string->bytevector "test:testpassword" "utf-8"))))
+                `(authorization . (basic . ,encoded))))
+
+            (test-equal "Miniflux initial admin API call is successful"
+              200
+              (begin
+                (wait-for-tcp-port #$forwarded-port marionette)
+                (#$retry-on-error
+                 (lambda ()
+                   (let-values (((response _)
+                                 (http-get #$(format #f "http://localhost:~A/v1/me" forwarded-port)
+                                           #:headers (list authorization-header)
+                                           #:decode-body? #t)))
+
+                     (response-code response)))
+                 #:times 10
+                 #:delay 2)))
+
+            (test-end)))))
+  (gexp->derivation (string-append name "-test") test))
+
+(define* (run-miniflux-socket-test name test-os)
+  (define os
+    (marionette-operating-system
+     test-os
+     #:imported-modules '((gnu services herd)
+                          (guix combinators))))
+
+  (define vm
+    (virtual-machine
+      (operating-system os)
+      (memory-size 512)))
+
+  (define test
+    (with-imported-modules '((gnu build marionette))
+      #~(begin
+          (use-modules (srfi srfi-64)
+                       (gnu build marionette))
+
+          (define marionette
+            (make-marionette (list #$vm)))
+
+          (test-runner-current (system-test-runner #$output))
+          (test-begin #$name)
+
+          (test-assert "Check socket file is created"
+            (wait-for-unix-socket "/var/run/miniflux/miniflux.sock" marionette))
+
+          (test-end))))
+  (gexp->derivation (string-append name "-test") test))
+
+(define %test-miniflux-admin-string
+  (system-test
+   (name "miniflux-admin-string")
+   (description "Run Miniflux with initial admin credentials as string.")
+   (value (run-miniflux-test name %miniflux-with-admin-as-string))))
+
+(define %test-miniflux-admin-file
+  (system-test
+   (name "miniflux-admin-file")
+   (description "Run Miniflux with initial admin credentials as file.")
+   (value (run-miniflux-test name %miniflux-with-admin-as-file))))
+
+(define %test-miniflux-socket
+  (system-test
+   (name "miniflux-socket")
+   (description "Run Miniflux on unix socket.")
+   (value (run-miniflux-socket-test name %miniflux-with-socket))))
diff --git a/po/packages/POTFILES.in b/po/packages/POTFILES.in
index 0dfbbd6e61b..9522bdc5c70 100644
--- a/po/packages/POTFILES.in
+++ b/po/packages/POTFILES.in
@@ -461,7 +461,6 @@ gnu/packages/nushell.scm
 gnu/packages/ocaml.scm
 gnu/packages/ocr.scm
 gnu/packages/onc-rpc.scm
-gnu/packages/openbox.scm
 gnu/packages/opencog.scm
 gnu/packages/openldap.scm
 gnu/packages/openstack.scm